ArticleInternational archives of occupational and environmental health2006
Subclinical effects of prenatal methylmercury exposure on cardiac autonomic function in Japanese children.
Article in International archives of occupational and environmental health, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- A Review on the Vagus Nerve and Autonomic Nervous System During Fetal Development: Searching for Critical Windows.Frontiers in neuroscience · 2021Pooled it
- Mercury Exposure and Heart Rate Variability: a Systematic Review.Current environmental health reports · 2015Pooled it
- Prenatal fluoride exposure, offspring visual acuity and autonomic nervous system function in 6-month-old infants.Environment international · 2024Article
- Use of occupancy modelling to identify sample sizes and waterbodies with fish exceeding mercury consumption advisory thresholds.Ecotoxicology (London, England) · 2021Article
- Factors influencing fish mercury concentrations in Iowa rivers.Ecotoxicology (London, England) · 2019Article
- Review
- Polycyclic aromatic hydrocarbons, brachial artery distensibility and blood pressure among children residing near an oil refinery.Environmental research · 2015Article
- Sex differences in the relationship between blood mercury concentration and metabolic syndrome risk.Journal of endocrinological investigation · 2015Article
- Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study.Environmental health : a global access science source · 2011Article
- Evaluation of the cardiovascular effects of methylmercury exposures: current evidence supports development of a dose-response function for regulatory benefits analysis.Environmental health perspectives · 2011Review
- Adverse effects of methylmercury: environmental health research implications.Environmental health perspectives · 2010Review
- In vivo methylmercury exposure induced long-lasting epileptiform activity in layer II/III neurons in cortical slices from the rat.Toxicology letters · 2010Article
- Methylmercury exposure and adverse cardiovascular effects in Faroese whaling men.Environmental health perspectives · 2009Article
- Cardiac autonomic activity and blood pressure among Nunavik Inuit adults exposed to environmental mercury: a cross-sectional study.Environmental health : a global access science source · 2008Article
- Effects of mercury vapor exposure on neuromotor function in Chinese miners and smelters.International archives of occupational and environmental health · 2007Article
- Assessment of the Cardiac Autonomic Nervous System in Mercury-Exposed Individuals via Post-Exercise Heart Rate Recovery.Medical principles and practice : international journal of the Kuwait University, Health Science CentreArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe subclinical effects of prenatal exposure to methylmercury from fish consumption on the cardiac autonomic function were assessed in 136 Japanese 7-year-old children recruited for this study.
methodsSamples of child's hair and dry umbilical cord preserved were collected, and hair mercury and cord tissue methylmercury concentrations were determined as current and prenatal exposure biomarkers, respectively. Cardiac autonomic indicators of parasympathetic and sympathetic activities were calculated from the electrocardiographic RR intervals measured.
resultsIn the children, the cord tissue methylmercury (0.017-0.367, median 0.089 microg/g) was not significantly correlated with the hair mercury (0.43-6.32, median 1.66 microg/g). The cord tissue methylmercury was related negatively to parasympathetic components of cardiac autonomic indicators (P < 0.05) and positively to sympathovagal indices (P < 0.05), even after correction for possible confounders such as age and sex, although the hair mercury was not significantly correlated with any cardiac autonomic indicators.
conclusionsDespite the potential limitations involved in the retrospective study, these findings suggest that prenatal methylmercury exposure (median of estimated maternal hair mercury at parturition, 2.24 microg/g) may be associated with reduced parasympathetic activity and/or sympathovagal shift.
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