ArticleEuropean journal of clinical pharmacology2006
The gap between evidence-based medicine and daily practice in the management of paediatric asthma. A pharmacy-based population study from The Netherlands.
Article in European journal of clinical pharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.European journal of clinical pharmacology · 2010Pooled it
- Current and novel approaches in the pharmacological treatment of hepatocellular carcinoma.World journal of gastroenterology · 2023Review
- Rationale and design of the PRegnancy and Infant DEvelopment (PRIDE) Study.Paediatric and perinatal epidemiology · 2013Article
- Cost considerations of therapeutic options for children with asthma.Paediatric drugs · 2012Article
- Assessment of pediatric asthma drug use in three European countries; a TEDDY study.European journal of pediatrics · 2011Article
- Prevalence, incidence and persistence of anti-asthma medication use in 2- to 29-year-olds: a nationwide prescription study.European journal of clinical pharmacology · 2010Article
- Prescription of respiratory medication without an asthma diagnosis in children: a population based study.BMC health services research · 2008Article
- Use of anti-asthmatic medications as a proxy for prevalence of asthma in children and adolescents in Norway: a nationwide prescription database analysis.European journal of clinical pharmacology · 2007Article
- Identification of asthmatic children using prescription data and diagnosis.European journal of clinical pharmacology · 2007Article
- Prescribed doses of inhaled steroids in Dutch children: too little or too much, for too short a time.British journal of clinical pharmacology · 2006Article
- British asthma patients are being misled.European journal of clinical pharmacology · 2006Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe evaluated the adherence to national guidelines for the treatment of asthma in childhood.
methodsPrescriptions for anti-asthma medication for children (0-14 years of age) were retrieved from the InterAction DataBase (IABD) for the year 2002. These were compared with recommendations found in national guidelines.
resultsAnti-asthma medication was prescribed for 3,612 children (5%) of the paediatric population. Inhaled medication was prescribed for 3,554 (98%) children. In 1,940 of 1,993 (97%) of the children under the age of 6 years pressurised metered dose inhalers (pMDIs) were given. Short-acting beta2-agonists had not been prescribed in the previous 2-year period in 559 children (15%), 543 children older than 8 years (36%) did not receive a prescription for a dry powder inhalator and 239 children (7%) had more than one type of inhalator. Long-acting beta2-agonists were prescribed in 396 children, but without concomitant inhaled corticosteroids (ICS) in 35 children (9%).
conclusionsInhalation therapy as the method of choice in asthma therapy and the use of pMDI in preschool children are widely accepted in the Netherlands. Not all children have been prescribed bronchodilators. Some children have more than one type of inhaler device and others use long-acting beta2-agonists not in combination with ICS. Although national and international guidelines about the treatment of asthma in children offer evidence-based advice, important principles are not followed. Effective interventions aimed at implementing existing guidelines into daily practice are urgently needed.
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