Evidence map›Paper›PMID 16365688›Full record

ArticleClinical rheumatology2006

Human foamy virus bel1 sequence in patients with autoimmune rheumatic diseases.

Kuang-Hui Sun, Hsiao-Yi Lin, Lee-Wen Chen, Hsiao-Yun Tai, Mei-Lin Lin, Chi-Kuang Feng, Jung-Sung Sung, Hsin-Fu Liu, Wu-Tse Liu

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Is there any relationship between human foamy virus infections and familial Mediterranean fever?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Kuang-Hui SunInstitute of Biotechnology in Medicine, School of Medical Technology and Engineering, National Yang-Ming University, Taipei, Taiwan, Republic of China. khsun@ym.edu.tw
Hsiao-Yi Lin
Lee-Wen Chen
Hsiao-Yun Tai
Mei-Lin Lin
Chi-Kuang Feng
Jung-Sung Sung
Hsin-Fu Liu
Wu-Tse Liu
National Yang Ming Chiao Tung University · TWNational Yang Ming University Hospital · TWTaipei Veterans General Hospital · TWMackay Memorial Hospital · TWNational Taiwan University of Science and Technology · TWTaipei Municipal YangMing Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the association between human foamy virus (HFV) with rheumatic autoimmune diseases remains controversial, this study was designed to determine the relationship between HFV and systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), or progressive systemic sclerosis (PSS). The bel1 and Pol sequences of HFV were measured by reverse transcriptase-polymerase chain reaction (RT-PCR) in plasma and by PCR in peripheral blood mononuclear cells (PBMC) from patients with SLE, RA, and PSS. Antibodies against Bel1 and Pol were assessed by enzyme-linked immunosorbent assay. Active HFV infections were detected by a Bel1-responsive indicator cell line. The bel1 sequence was detected in the plasma (SLE 59, RA 32, and PSS 63%) and PBMC (SLE 54, RA 71, and PSS 57%). However, active HFV infection existed only in patients with the bel1 sequence in both plasma and PBMC. In SLE patients, antibodies against Bel1 (7.1%) and Pol (4.5%) were also detected. The results suggest a possible association between HFV infection and these autoimmune rheumatic diseases.

Indexed as

AdolescentAdultAgedArthritis, RheumatoidAutoimmune DiseasesChildDNA-Binding ProteinsDNA, ViralHumansLeukocytes, MononuclearLupus Erythematosus, SystemicMiddle AgedRetroviridae InfectionsRetroviridae ProteinsRNA, ViralScleroderma, Systemicbel1 protein, Human foamy virusDNA-Binding ProteinsDNA, ViralRetroviridae ProteinsRNA, ViralTrans-Activators

Identifiers

PMID16365688
OpenAlexW1999871267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.