Evidence map›Paper›PMID 16364749›Full record

ReviewVirology2006

Translational control in positive strand RNA plant viruses.

Theo W Dreher, W Allen Miller

Abstract readReview
In one paragraph

Review in Virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. RNAViruses · 2026
    Review
  2. Targeted knockout of a host peroxisomal peptidase confers field resistance to maize lethal necrosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  17. The NovelFrontiers in microbiology · 2021
    Article
  18. Article
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Theo W DreherDepartment of Microbiology and Center for Gene Research and Biotechnology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA. theo.dreher@oregonstate.edu
W Allen Miller

Funding

Control of cap-independent translation by a viral 3' UTRR01GM067104 · NIGMS · IOWA STATE UNIVERSITY · PI MILLER, WYATT ALLEN · 2003 to 2016
$3.0M
NIGMS NIH HHS R01 GM067104NIGMS NIH HHS R01-GM067104
6 · The paper itself

Abstract

The great variety of genome organizations means that most plant positive strand viral RNAs differ from the standard 5'-cap/3'-poly(A) structure of eukaryotic mRNAs. The cap and poly(A) tail recruit initiation factors that support the formation of a closed loop mRNA conformation, the state in which translation initiation is most efficient. We review the diverse array of cis-acting sequences present in viral mRNAs that compensate for the absence of a cap, poly(A) tail, or both. We also discuss the cis-acting sequences that control translation strategies that both amplify the coding potential of a genome and regulate the accumulations of viral gene products. Such strategies include leaky scanning initiation of translation of overlapping open reading frames, stop codon readthrough, and ribosomal frameshifting. Finally, future directions for research on the translation of plant positive strand viruses are discussed.

Indexed as

Genome, ViralProtein Biosynthesis3' Untranslated RegionsCodon, TerminatorFrameshifting, RibosomalPlant VirusesRNA CapsRNA VirusesViral Proteins3' Untranslated RegionsCodon, TerminatorRNA CapsViral Proteins

Identifiers

PMID16364749
PMCPMC1847782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.