Evidence map›Paper›PMID 16362723›Full record

ReviewJournal of muscle research and cell motility2006

Interaction of kinesin motors, microtubules, and MAPs.

A Marx, J Müller, E-M Mandelkow, A Hoenger, E Mandelkow

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Long Noncoding RNAs in Taxane Resistance of Breast Cancer.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Neurological manifestations of COVID-19 in patients: from path physiology to therapy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Single-molecule inhibition of human kinesin by adociasulfate-13 and -14 from the sponge Cladocroce aculeata.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Trafficking guidance receptors.Cold Spring Harbor perspectives in biology · 2010
    Review
  17. Article
  18. Review
  19. Review
  20. Structure of the kinesin13-microtubule ring complex.Structure (London, England : 1993) · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A MarxMax-Planck-Unit for Structural Molecular Biology, Notkestrasse 85, 22607, Hamburg, Germany.
J Müller
E-M Mandelkow
A Hoenger
E Mandelkow
Max Planck Unit for Structural Molecular Biology · DEEuropean Molecular Biology Laboratory · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinesins are a family of microtubule-dependent motor proteins that carry cargoes such as vesicles, organelles, or protein complexes along microtubules. Here we summarize structural studies of the "conventional" motor protein kinesin-1 and its interactions with microtubules, as determined by X-ray crystallography and cryo-electron microscopy. In particular, we consider the docking between the kinesin motor domain and tubulin subunits and summarize the evidence that kinesin binds mainly to beta tubulin with the switch-2 helix close to the intradimer interface between alpha and beta tubulin.

Indexed as

AnimalsCrystallography, X-RayHumansKinesinsMicrotubule-Associated ProteinsMicrotubulesProtein BindingProtein Structure, SecondaryProtein Structure, TertiaryProtein SubunitsTubulinKinesinsMicrotubule-Associated ProteinsProtein SubunitsTubulin

Identifiers

PMID16362723
OpenAlexW2083922364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.