ReviewPsychopharmacology2006
Action by and sensitivity to neuroactive steroids in menstrual cycle related CNS disorders.
Review in Psychopharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 56 citations in OpenAlex.
- How progesterone impairs memory for biologically salient stimuli in healthy young women.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Trial
- Dysbiosis of the Human Oral Microbiome During the Menstrual Cycle and Vulnerability to the External Exposures of Smoking and Dietary Sugar.Frontiers in cellular and infection microbiology · 2021Article
- A novel therapeutic approach for treatment of catamenial epilepsy.Neurobiology of disease · 2018Article
- Article
- The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders.Psychopharmacology · 2014Review
- Neurosteroids and GABAergic signaling in health and disease.Biomolecular concepts · 2013Review
- Changes in brain size during the menstrual cycle.PloS one · 2011Article
- Beyond the HPA Axis: Progesterone-Derived Neuroactive Steroids in Human Stress and Emotion.Frontiers in endocrinology · 2011Article
- Neurosteroids and GABA-A Receptor Function.Frontiers in endocrinology · 2011Article
- Menstrual cycle-related exacerbation of disease.American journal of obstetrics and gynecology · 2010Review
- Influence of 17beta-estradiol and progesterone on GABAergic gene expression in the arcuate nucleus, amygdala and hippocampus of the rhesus macaque.Brain research · 2010Article
- Sex steroid-related candidate genes in psychiatric disorders.Journal of psychiatry & neuroscience : JPN · 2008Review
- Progesterone receptors: form and function in brain.Frontiers in neuroendocrinology · 2008Review
- Progesterone selectively increases amygdala reactivity in women.Molecular psychiatry · 2008Article
- Mechanisms of neurosteroid interactions with GABA(A) receptors.Pharmacology & therapeutics · 2007Review
- Luteal-phase accentuation of acoustic startle response in women with premenstrual dysphoric disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroactive steroids are a large group of substances having effect in the brain and on brain function. The steroids most studied are allopregnanolone (ALLO), tetrahydrodesoxycorticosterone (THDOC), pregnenolone sulfate (PS) dihydroepiandrosteronesulfate (DHEAS), and estradiol (E2). ALLO and THDOC are called gamma-aminobutyric acid (GABA) steroids as they are positive modulators of the GABAA receptor in a similar way as benzodiazepines, barbiturates, and alcohol. GABA steroids not only have similar behavioral effects as benzodiazepines and barbiturates but, possibly, also similar adverse effects as well. This review aims to elucidate the possible role that neuroactive steroids play in the development of mood disorders in women. One of the most clear-cut examples of the interaction between mood, neuroactive steroids, and the GABA system is premenstrual dysphoric disorder (PMDD), which is a cluster of negative mood symptoms occurring during the luteal phase of the menstrual cycle in 2-6% of reproductive women. Furthermore, certain women also experience adverse mood effects during sequential progestin addition to postmenopausal estrogen treatment, which is why the role of neuroactive steroids in postmenopausal women is also addressed in this review.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.