Evidence map›Paper›PMID 16362320›Full record

ArticleHistochemistry and cell biology2006

Ca2+ -activated K+ channels of the BK-type in the mouse brain.

Ulrike Sausbier, Matthias Sausbier, Claudia A Sailer, Claudia Arntz, Hans-Günther Knaus, Winfried Neuhuber, Peter Ruth

Abstract read
PubMed Publisher
In one paragraph

Article in Histochemistry and cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 160 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. BK channels sustain neuronal CaCellular and molecular life sciences : CMLS · 2023
    Article
  6. CaInternational journal of molecular sciences · 2023
    Review
  7. Locus Coeruleus Neurons' Firing Pattern Is Regulated by ERG Voltage-Gated KInternational journal of molecular sciences · 2022
    Article
  8. Article
  9. Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Protein kinase Cγ in cerebellar Purkinje cells regulates CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. BK Channel Regulation of Afterpotentials and Burst Firing in Cerebellar Purkinje Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  15. Comparison of KHandbook of experimental pharmacology · 2021
    Article
  16. Article
  17. Article
  18. The Journal of general physiology · 2019
    Review
  19. Article
  20. Expanding the Phenotype of HomozygousBalkan medical journal · 2018
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ulrike SausbierPharmakologie und Toxikologie, Pharmazeutisches Institut der Universität Tübingen, Tübingen, Germany.
Matthias Sausbier
Claudia A Sailer
Claudia Arntz
Hans-Günther Knaus
Winfried Neuhuber
Peter Ruth
University of Tübingen · DEInnsbruck Medical University · ATFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An antibody against the 442 carboxy-terminal amino acids of the BK channel alpha-subunit detects high immunoreactivity within the telencephalon in cerebral cortices, olfactory bulb, basal ganglia and hippocampus, while lower levels are found in basal forebrain regions and amygdala. Within the diencephalon, high density was found in nuclei of the ventral and dorsal thalamus and the medial habenular nucleus, and low density in the hypothalamus. The fasciculus retroflexus and its termination in the mesencephalic interpeduncular nucleus are prominently stained. Other mesencephalic expression sites are periaquaeductal gray and raphe nuclei. In the rhombencephalon, BK channels are enriched in the cerebellar cortex and in the locus coeruleus. Strong immunoreactivity is also contained in the vestibular nuclei, but not in cranial nerves and their intramedullary course of their roots. On the cellular level, BK channels show pre- and postsynaptic localizations, i.e., in somata, dendrites, axons and synaptic terminals.

Indexed as

Brain ChemistryAnimalsAntibodiesBrainImmunohistochemistryLarge-Conductance Calcium-Activated Potassium ChannelsMiceMice, Mutant StrainsPotassium Channels, Calcium-ActivatedTissue DistributionAntibodiesLarge-Conductance Calcium-Activated Potassium ChannelsPotassium Channels, Calcium-Activated

Identifiers

PMID16362320
OpenAlexW2126219184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.