ArticleNucleic acids research2005
Dynamic regulation of replication independent deposition of histone H3 in fission yeast.
Article in Nucleic acids research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 47 citations in OpenAlex.
- The ortholog of human DNAJC9 promotes histone H3-H4 degradation and is counteracted by Asf1 in fission yeast.Nucleic acids research · 2025Article
- RebL1 is required for macronuclear structure stability and gametogenesis inMarine life science & technology · 2024Article
- Chromatin accessibility profiling in Neurospora crassa reveals molecular features associated with accessible and inaccessible chromatin.BMC genomics · 2021Article
- Article
- RNAi drives nonreciprocal translocations at eroding chromosome ends to establish telomere-free linear chromosomes.Genes & development · 2018Article
- A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin.Genome research · 2015Article
- Genome-wide identification, evolutionary, and expression analyses of histone H3 variants in plants.BioMed research international · 2015Article
- Chromosome boundary elements and regulation of heterochromatin spreading.Cellular and molecular life sciences : CMLS · 2014Review
- Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity.Nature structural & molecular biology · 2014Article
- Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.The Journal of biological chemistry · 2013Article
- HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin.Nature structural & molecular biology · 2013Article
- Dynamic deposition of histone variant H3.3 accompanies developmental remodeling of the Arabidopsis transcriptome.PLoS genetics · 2012Article
- Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe.Molecular and cellular biology · 2011Article
- The double face of the histone variant H3.3.Cell research · 2011Review
- Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci.Molecular cell · 2011Article
- Genome-wide measurement of histone H3 replacement dynamics in yeast.Methods in molecular biology (Clifton, N.J.) · 2011Article
- Topoisomerase I regulates open chromatin and controls gene expression in vivo.The EMBO journal · 2010Article
- New functions for an old variant: no substitute for histone H3.3.Current opinion in genetics & development · 2010Review
- Recombination-induced tag exchange to track old and new proteins.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Genome-wide views of chromatin structure.Annual review of biochemistry · 2009Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, a histone H3 variant in Drosophila and humans, the H3.3 protein, was shown to replace canonical H3 in active chromatin in a replication-independent (RI) manner. In the fission yeast Schizosaccharomyces pombe, there exists a single form of H3, which is equivalent to H3.3 and is thought to participate in both replication-independent (RI) and replication-coupled (RC) nucleosome assembly. In this study, we show that RI deposition of H3 at heterochromatic regions is consistently lower than that at a gene-free euchromatic region, and deletion of the conserved heterochromatin-specific proteins Swi6 or Clr4 markedly increases RI deposition at heterochromatic regions such as the silent mating-type loci or centromeres. These results clearly show that RI deposition of H3 occurs preferentially in euchromatic regions. We also observed that RI deposition of H3 could be increased at the thi3(+) gene when transcription is induced, indicating transcription further facilitates RI deposition of H3. Taken together, these observations demonstrate that selective deposition of histone H3.3 at transcriptionally active chromatin by the RI assembly pathway is conserved in fission yeast and, thus, our data support an essential role of histone H3 replacement in maintaining active chromatin among diverse eukaryotic organisms ranging from fission yeast to humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.