Evidence map›Paper›PMID 16356945›Full record

Trial reportBMJ (Clinical research ed.)2006

Partner notification of chlamydia infection in primary care: randomised controlled trial and analysis of resource use.

Nicola Low, Anne McCarthy, Tracy E Roberts, Mia Huengsberg, Emma Sanford, Jonathan A C Sterne, John Macleod, Chris Salisbury, Karl Pye, Aisha Holloway and 6 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00112255 (Partner Notification for Chlamydia in Primary Care), which is not on this map. Cited by 25 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 11 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00112255 phase3completednot on this map

Partner Notification for Chlamydia in Primary Care: Randomised Controlled Trial and Economic Evaluation

TypeinterventionalSponsorUniversity of BristolRan2001 to 2002Enrolled214ConditionsChlamydia InfectionsArmsPractice nurse-led partner notification, Referral to specialist genitourinary clinic
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 11 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Guideline
  8. Partner notification.BMJ clinical evidence · 2009
    Pooled it
  9. Chlamydia (uncomplicated, genital).BMJ clinical evidence · 2008
    Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Nicola LowDepartment of Social Medicine, University of Bristol, Bristol BS8 2PR. low@ispm.unibe.ch
Anne McCarthy
Tracy E Roberts
Mia Huengsberg
Emma Sanford
Jonathan A C Sterne
John Macleod
Chris Salisbury
Karl Pye
Aisha Holloway
Andrea Morcom
Rita Patel
Suzanne M Robinson
Paddy Horner
Pelham M Barton
Matthias Egger
University of Birmingham · GBUniversity of Bristol · GBNorth Bristol NHS Trust · GBInstitute of Social and Preventive Medicine · CHPrimary Health Care · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of a practice nurse led strategy to improve the notification and treatment of partners of people with chlamydia infection.

designRandomised controlled trial.

setting27 general practices in the Bristol and Birmingham areas.

participants140 men and women with chlamydia (index cases) diagnosed by screening of a home collected urine sample or vulval swab specimen.

interventionsPartner notification at the general practice immediately after diagnosis by trained practice nurses, with telephone follow up by a health adviser; or referral to a specialist health adviser at a genitourinary medicine clinic.

main outcome measuresPrimary outcome was the proportion of index cases with at least one treated sexual partner. Specified secondary outcomes included the number of sexual contacts elicited during a sexual history, positive test result for chlamydia six weeks after treatment, and the cost of each strategy in 2003 sterling prices.

results65.3% (47/72) of participants receiving practice nurse led partner notification had at least one partner treated compared with 52.9% (39/68) of those referred to a genitourinary medicine clinic (risk difference 12.4%, 95% confidence interval -1.8% to 26.5%). Of 68 participants referred to the clinic, 21 (31%) did not attend. The costs per index case were 32.55 pounds sterling for the practice nurse led strategy and 32.62 pounds sterling for the specialist referral strategy.

conclusionPractice based partner notification by trained nurses with telephone follow up by health advisers is at least as effective as referral to a specialist health adviser at a genitourinary medicine clinic, and costs the same. Trial registration Clinical trials: NCT00112255.

Indexed as

Chlamydia InfectionsContact TracingCosts and Cost AnalysisEnglandFamily PracticeFemaleHealth ResourcesHumansMaleNurse PractitionersReferral and ConsultationSpecimen Handling

Identifiers

PMID16356945
PMCPMC1325126
OpenAlexW2158458739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.