Evidence map›Paper›PMID 16356276›Full record

ReviewGenome biology2005

The expansin superfamily.

Javier Sampedro, Daniel J Cosgrove

Open access · bronzeAbstract readReview
In one paragraph

Review in Genome biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 288 papers.

0numbers the graph read from it
0cells of the map it votes in
288citing papers in PubMed
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

288 citing papers in PubMed, 701 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Functional Analysis ofPlants (Basel, Switzerland) · 2026
    Article
  8. Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026
    Article
  9. Review
  10. A single-domain expansin-like protein fromProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Pathogen-Mediated Cell Fusion and Actin Cytoskeleton.Advances in experimental medicine and biology · 2026
    Review
  13. Comparative multi "omics" profiling ofFrontiers in plant science · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Overexpression of the Wild Soybean Expansin GenePlants (Basel, Switzerland) · 2025
    Article
  20. Article

228 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Javier SampedroDepartment of Biology, Pennsylvania State University, 208 Mueller Lab, University Park, PA 16870, USA.
Daniel J Cosgrove
Pennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expansin superfamily of plant proteins is made up of four families, designated alpha-expansin, beta-expansin, expansin-like A and expansin-like B. alpha-Expansin and beta-expansin proteins are known to have cell-wall loosening activity and to be involved in cell expansion and other developmental events during which cell-wall modification occurs. Proteins in these two families bind tightly to the cell wall and their activity is typically assayed by their stimulation of cell-wall extension and stress relaxation; no bona fide enzymatic activity has been detected for these proteins. Alpha-expansin proteins and some, but not all, beta-expansin proteins are implicated as catalysts of 'acid growth', the enlargement of plant cells stimulated by low extracellular pH. A divergent group of beta-expansin genes are expressed at high levels in the pollen of grasses but not of other plant groups. They probably function to loosen maternal cell walls during growth of the pollen tube towards the ovary. All expansins consist of two domains; domain 1 is homologous to the catalytic domain of proteins in the glycoside hydrolase family 45 (GH45); expansin domain 2 is homologous to group-2 grass pollen allergens, which are of unknown biological function. Experimental evidence suggests that expansins loosen cell walls via a nonenzymatic mechanism that induces slippage of cellulose microfibrils in the plant cell wall.

Indexed as

Multigene FamilyBiological EvolutionGene Expression Regulation, PlantGenes, PlantModels, MolecularPlant Proteinsexpansin protein, plantPlant Proteins

Identifiers

PMID16356276
PMCPMC1414085
OpenAlexW2103249145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.