ReviewThe AAPS journal2005
Population pharmacokinetics/pharmacodynamics of anesthetics.
Review in The AAPS journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Prediction Accuracy in Multivariate Repeated-Measures Bayesian Forecasting Models with Examples Drawn from Research on Sleep and Circadian Rhythms.Computational and mathematical methods in medicine · 2016Article
- Pharmacokinetic-pharmacodynamic modelling in anaesthesia.British journal of clinical pharmacology · 2015Review
- The determinants of propofol induction time in anesthesia.Korean journal of anesthesiology · 2013Article
- Using remifentanil in mechanically ventilated rats to provide continuous analgosedation.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012Article
- Circulatory model of vascular and interstitial distribution kinetics of rocuronium: a population analysis in patients.Journal of pharmacokinetics and pharmacodynamics · 2011Article
- A tool predicting future mean arterial blood pressure values improves the titration of vasoactive drugs.Journal of clinical monitoring and computing · 2010Article
- Determination of Induction Time in Adult Patients with Valvular Heart Disease.Indian heart journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this article we review how population pharmacokinetic/pharmacodynamic (PD) modeling has evolved in the specialty of anesthesiology, how anesthesiology benefited from the mixed-effects approach, and which features of modeling need careful attention. Key articles from the anesthesiology literature are selected to discuss the modeling of typical anesthesiological PD end points, such as level of consciousness and analgesia, interactions between hypnotics and analgesics, estimation with poor and sometimes rich data sets from populations of various sizes, covariate detection, covariances between random effects, and Bayesian forecasting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.