ArticleApplied and environmental microbiology1993
Enhanced Carotenoid Biosynthesis by Oxidative Stress in Acetate-Induced Cyst Cells of a Green Unicellular Alga, Haematococcus pluvialis.
Article in Applied and environmental microbiology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
54 citing papers in PubMed, 351 citations in OpenAlex.
- Enhanced Production of Astaxanthin and Zeaxanthin by Paracoccus Sp. LL1 Through Random Mutagenesis.Biotechnology and applied biochemistry · 2026Article
- Light intensity influences carotenoid accumulation and modulates the expression of photosynthetic genes in Euglena sanguinea.Photosynthesis research · 2025Article
- Effects of Four Organic Carbon Sources on the Growth and Astaxanthin Accumulation ofLife (Basel, Switzerland) · 2023Article
- Microalgae as a Source of Valuable Phenolic Compounds and Carotenoids.Molecules (Basel, Switzerland) · 2022Review
- Changes in Carbon Partitioning and Pattern of Antioxidant Enzyme Activity Induced by Arginine Treatment in the Green Microalga Dunaliella salina Under Long-Term Salinity.Microbial ecology · 2022Article
- Optimization of microbial cell factories for astaxanthin production: Biosynthesis and regulations, engineering strategies and fermentation optimization strategies.Synthetic and systems biotechnology · 2022Review
- Improved Productivity of Astaxanthin from PhotosensitiveMarine drugs · 2022Article
- A Fast-Growing Oleaginous Strain ofLife (Basel, Switzerland) · 2022Article
- Identification of a RelA/SpoT Homolog and Its Possible Role in the Accumulation of Astaxanthin inFrontiers in plant science · 2022Article
- Microalgae Xanthophylls: From Biosynthesis Pathway and Production Techniques to Encapsulation Development.Foods (Basel, Switzerland) · 2021Review
- E/Z isomerization of astaxanthin and its monoesters in vitro under the exposure to light or heat and in overilluminated Haematococcus pluvialis cells.Bioresources and bioprocessing · 2021Article
- NaCl Promotes the Efficient Formation ofMarine drugs · 2021Article
- The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis.Biotechnology for biofuels · 2021Review
- Assessing the Potential of Algae Extracts for Extending the Shelf Life of Rainbow Trout (Foods (Basel, Switzerland) · 2021Article
- Article
- Astaxanthin accumulation in the green microalgaBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- Photooxidative stress-inducible orange and pink water-soluble astaxanthin-binding proteins in eukaryotic microalga.Communications biology · 2020Article
- Assessment of Mineral and Phenolic Profiles and Their Association with the Antioxidant, Cytotoxic Effect, and Antimicrobial Potential ofPlants (Basel, Switzerland) · 2020Article
- Enhanced Biomass and Astaxanthin Production ofMarine drugs · 2020Article
- Natural Communities of Carotenogenic Chlorophyte Haematococcus lacustris and Bacteria from the White Sea Coastal Rock Ponds.Microbial ecology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a green alga, Haematococcus pluvialis, a morphological change of vegetative cells into cyst cells was rapidly induced by the addition of acetate or acetate plus Fe to the vegetative growth phase. Accompanied by cyst formation, algal astaxanthin formation was more enhanced by the addition of acetate plus Fe than by the addition of acetate alone. Encystment and enhanced carotenoid biosynthesis were inhibited by either actinomycin D or cycloheximide. However, after cyst formation was induced by the addition of acetate alone, carotenoid formation could be enhanced with the subsequent addition of Fe even in the presence of the inhibitors. The Fe -enhanced carotenogenesis was inhibited by potassium iodide, a scavenger for hydroxyl radical, suggesting that hydroxyl radical formed by an iron-catalyzed Fenton reaction may be required for enhanced carotenoid biosynthesis. Moreover, it was demonstrated that four active oxygen species, singlet oxygen, superoxide anion radical, hydrogen peroxide, and peroxy radical, were capable of replacing Fe in its role in the enhanced carotenoid formation in the acetate-induced cyst. From these results, it was concluded that oxidative stress is involved in the posttranslational activation of carotenoid biosynthesis in acetate-induced cyst cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.