Evidence map›Paper›PMID 16344967›Full record

ArticleInternational journal of legal medicine2006

DXS10079, DXS10074 and DXS10075 are STRs located within a 280-kb region of Xq12 and provide stable haplotypes useful for complex kinship cases.

Sandra Hering, Christa Augustin, Jeanett Edelmann, Micaela Heidel, Jan Dressler, Heike Rodig, Eberhard Kuhlisch, Reinhard Szibor

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Article in International journal of legal medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  16. Allele and haplotype diversity of X-chromosomal STRs in Ivory Coast.International journal of legal medicine · 2011
    Article
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  19. Analysis of 21 X-chromosomal STRs in an Algerian population sample.International journal of legal medicine · 2010
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandra HeringInstitut für Rechtsmedizin, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Christa Augustin
Jeanett Edelmann
Micaela Heidel
Jan Dressler
Heike Rodig
Eberhard Kuhlisch
Reinhard Szibor

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evaluation of the short tandem repeat (STR) markers DXS10079, DXS10074 and DXS10075 was amended to establish a STR cluster spanning a genetic distance<1 cM. These three STRs are located within a 280-kb region at Xq12 and provide stable haplotypes useful for solving complex kinship cases. Theoretically, this cluster could give rise to 2,548 different haplotypes in the German population and the genotyping of 781 men revealed the presence of 172 haplotypes. Since the three STRs were shown to be in strong linkage disequilibrium (LD), haplotype frequencies cannot be computed on the basis of a single locus allele frequency alone but have to be estimated directly. Here, we present data on linkage, haplotype frequencies and LD in a German population. Further clusters from other regions of the X chromosome will be published in the future to cover the chromosome with a well-structured network of highly informative sites.

Indexed as

Chromosomes, Human, XHaplotypesPedigreeTandem Repeat SequencesDNA FingerprintingDNA PrimersFemaleForensic GeneticsGene FrequencyGenetic MarkersGenetics, PopulationHumansMaleMeiosisSequence Analysis, DNADNA PrimersGenetic Markers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.