ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2006
Determinants of health-related quality of life in women with vertebral fractures.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03263585 (Identification and Treatment of Back Pain in Elderly Women With Osteoporosis), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identification and Treatment of Back Pain in Elderly Women With Osteoporosis
Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- The Effects of Home Exercise in Older Women With Vertebral Fractures: A Pilot Randomized Controlled Trial.Physical therapy · 2020Trial
- Eldecalcitol reduces the risk of severe vertebral fractures and improves the health-related quality of life in patients with osteoporosis.Journal of bone and mineral metabolism · 2013Trial
- Zoledronic acid results in better health-related quality of life following hip fracture: the HORIZON-Recurrent Fracture Trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011Trial
- Balloon kyphoplasty in the treatment of metastatic disease of the spine: a 2-year prospective evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2008Trial
- Modelling the factors associated with quality of life in women with osteoporosis: A cross-sectional study.Global epidemiology · 2024Article
- A model of health education and management for osteoporosis prevention.Experimental and therapeutic medicine · 2016Article
- Depression is associated with increased incidence of osteoporotic thoracolumbar fracture in postmenopausal women: a prospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
- Health-related Quality of Life in Accordance with Fracture History and Comorbidities in Korean Patients with Osteoporosis.Journal of bone metabolism · 2016Article
- A painful, never ending story: older women's experiences of living with an osteoporotic vertebral compression fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- Effective osteoporosis treatment with teriparatide is associated with enhanced quality of life in postmenopausal women with osteoporosis: the European Forsteo Observational Study.BMC musculoskeletal disorders · 2013Observational
- Quality of life measurements in patients with osteoporosis and fractures.Clinics (Sao Paulo, Brazil) · 2012Review
- A striving for independence: a qualitative study of women living with vertebral fracture.BMC nursing · 2010Article
- Psychological state, quality of life, and body composition in postmenopausal women with osteoporosis in Lithuania.Archives of osteoporosis · 2009Article
- Health-related quality of life after vertebral or hip fracture: a seven-year follow-up study.BMC musculoskeletal disorders · 2009Article
- Measurement equivalence of osteoporosis-specific and general quality-of-life instruments in Aboriginal and non-Aboriginal women.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Health-related quality of life (HRQL) is an important consideration in the management of patients with vertebral fractures. The purpose of this study was to examine patient-related factors that contribute to HRQL after vertebral fractures, including co-morbidities, medications, fracture history, family disease history, demographics, exercise, education and living environment. A total of 1,129 post-menopausal women (mean age 67.2, SD 11.9 years) was studied from the Canadian Database of Osteoporosis and Osteopenia (CANDOO). HRQL was measured using the mini-osteoporosis quality of life questionnaire (mini-OQLQ). Separate multivariable linear regression analyses [parameter estimates and corresponding 95% confidence intervals (CI)] were performed for each of the five mini-OQLQ domains: symptoms, physical functioning, emotional functioning, activities of daily living and leisure domains. A strong positive association was found between HRQL and post-secondary education, a family history of osteoporosis, working and thiazide therapy. Exercise improved HRQL; however, several hours a week were required to be meaningful. Living in long-term care had the most marked negative effect on HRQL. Smoking, past surgery of the hip or spine, sedatives, anticonvulsants, atherosclerotic disease and hypertension were also associated with a substantially decreased HRQL across several domains. Calcium channel-blockers, chemotherapy, corticosteroids, diabetes, migraines, the number of non-vertebral fractures and falls had a negative impact on selected domains. We demonstrated that several modifiable factors influence HRQL in patients with vertebral fractures, and physicians should be aware of these and other markers of reduced HRQL to enhance patient care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.