ArticleJournal of perinatology : official journal of the California Perinatal Association2006
Sustained reductions in neonatal nosocomial infection rates following a comprehensive infection control intervention.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Antimicrobial-impregnated central venous catheters for prevention of catheter-related bloodstream infection in newborn infants.The Cochrane database of systematic reviews · 2015Pooled it
- Patient isolation measures for infants with candida colonization or infection for preventing or reducing transmission of candida in neonatal units.The Cochrane database of systematic reviews · 2011Pooled it
- Decrease in healthcare-associated infection rates in preterm infants-longitudinal data from 15 years of nationwide surveillance in Germany.Infection control and hospital epidemiology · 2026Article
- Evaluation of a novel reprocessed bCPAP system on sepsis rates among preterm neonates with respiratory distress: a randomized controlled trial.Frontiers in pediatrics · 2025Article
- Knowledge, attitudes, and readiness about critical antimicrobial resistant organisms among healthcare workers at colonial war memorial hospital in Fiji: a pre and post intervention study.Antimicrobial resistance and infection control · 2024Article
- A Quality Improvement Bundle to Improve Outcomes in Extremely Preterm Infants in the First Week.Pediatrics · 2022Article
- Challenges and opportunities for antibiotic stewardship among preterm infants.Archives of disease in childhood. Fetal and neonatal edition · 2019Review
- Late-onset Sepsis in Extremely Premature Infants: 2000-2011.The Pediatric infectious disease journal · 2017Article
- Sustained Reduction in Bloodstream Infections in Infants at a Large Tertiary Care Neonatal Intensive Care Unit.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2016Article
- Nosocomial infection reduction in VLBW infants with a statewide quality-improvement model.Pediatrics · 2011Article
- Understanding the significance of Staphylococcus epidermidis bacteremia in babies and children.Current opinion in infectious diseases · 2010Review
- Nosocomial infection in small for gestational age newborns with birth weight <1500 g: a multicentre analysis.Archives of disease in childhood. Fetal and neonatal edition · 2007Article
- Eliminating nosocomial infections in the NICU: everyone's duty.Journal of perinatology : official journal of the California Perinatal Association · 2006Article
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5 authors at 1 institution in 1 country.
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Abstract
objectiveNosocomial infections (NI) are a frequent and important cause of morbidity and mortality in newborn infants who receive intensive care. We sought to determine if comprehensive infection control (CIC) measures decrease rates in a large neonatal intensive care nursery.
methodsSingle center interventional study. The CIC intervention consisted of increasing nursing and physician education and awareness of infection rates, establishing common improvement goals, training in hand and environment care, and implementing a specialty nursing team for central venous and arterial catheter care. Demographic and microbiology information for all infants admitted to the NICU from January 1, 1999 to December 31, 2000 established baseline data. The intervention period was during January and February 2001. The postintervention period was March 1, 2001 to February 29, 2004. The main outcome measure was the rate of blood, cerebrospinal and/or urinary tract bacterial infections per 1000 hospital days.
resultsBaseline infection rate was 8.5 per 1000 hospital days. The NI rate fell 26% (P=0.002) from baseline in the first year and 29% (P<0.001) in the second and third years after the CIC intervention. The reduction in total NI was due mostly to a 46% fall in coagulase-negative Staphylococcus infection rate (P<0.001); however, rates of all other organisms also fell by 21% (P=0.05).
conclusionsCIC measures can reduce bacterial and fungal NI rates. This effect has been sustained for 3 years following the intervention.
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