Evidence map›Paper›PMID 16335534›Full record

ReviewMolecular and cellular biochemistry2005

Casein kinase 2, circadian clocks, and the flight from mutagenic light.

Ravi Allada, Rose-Anne Meissner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Physiological regulation of the epithelial NaAmerican journal of physiology. Renal physiology · 2018
    Article
  7. Article
  8. Circadian molecular clock in lung pathophysiology.American journal of physiology. Lung cellular and molecular physiology · 2015
    Review
  9. Article
  10. Mining CK2 in cancer.PloS one · 2014
    Article
  11. Article
  12. Article
  13. CK2α is essential for embryonic morphogenesis.Molecular and cellular biochemistry · 2011
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ravi AlladaDepartment of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA. r-allada@northwestern.edu
Rose-Anne Meissner
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian clocks play a fundamental role in biology and disease. Much has been learned about the molecular underpinnings of these biological clocks from genetic studies in model organisms, such as the fruit fly, Drosophila melanogaster. Here we review the literature from our lab and others that establish a role for the protein kinase CK2 in Drosophila clock timing. Among the clock genes described thus far, CK2 is unique in its involvement in plant, fungal, as well as animal circadian clocks. We propose that this reflects an ancient, conserved function for CK2 in circadian clocks. CK2 and other clock genes have been implicated in cellular responses to DNA damage, particularly those induced by ultraviolet (UV) light. The finding of a dual function of CK2 in clocks and in UV responses supports the notion that clocks evolved to assist organisms in avoiding the mutagenic effects of daily sunlight.

Indexed as

Circadian RhythmMutationAnimalsCasein Kinase IIDNA DamageDrosophila melanogasterPhosphorylationUltraviolet RaysCasein Kinase II

Identifiers

PMID16335534
OpenAlexW2020451511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.