HSP60 expression during carcinogenesis: a molecular "proteus" of carcinogenesis?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression.Cells · 2023
   Article
2. Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol.Bioorganic & medicinal chemistry · 2022
   Article
3. Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics.Frontiers in molecular biosciences · 2018
   Review
4. Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.Cell stress & chaperones · 2016
   Article
5. The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.Oncotarget · 2016
   Article
6. CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.Cell stress & chaperones · 2016
   Article
7. The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis.Journal of molecular biology · 2015
   Review
8. Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.European journal of histochemistry : EJH · 2013
   Article
9. Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60).PloS one · 2013
   Article
10. Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.Journal of cellular biochemistry · 2012
    Article
11. Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer.The FEBS journal · 2011
    Article
12. Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis.Cell stress & chaperones · 2010
    Article
13. Chlamydia trachomatis infection and anti-Hsp60 immunity: the two sides of the coin.PLoS pathogens · 2009
    Review
14. Protein profile of human hepatocarcinoma cell line SMMC-7721: identification and functional analysis.World journal of gastroenterology · 2007
    Article

Corrections and comments

• Comment on
  Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications.2005

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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