ArticleApplied and environmental microbiology2005
Transcriptional response of Saccharomyces cerevisiae to desiccation and rehydration.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 98 citations in OpenAlex.
- Article
- Hemolysin III drives neuroinvasion and meningitis while impacting desiccation resilience inApplied and environmental microbiology · 2025Article
- How to Survive without Water: A Short Lesson on the Desiccation Tolerance of Budding Yeast.International journal of molecular sciences · 2024Review
- Deciphering the mechanism of anhydrobiosis in the entomopathogenic nematode Heterorhabditis indica through comparative transcriptomics.PloS one · 2022Article
- Effects of rehydration on physiological and transcriptional responses of a water-stressed rhizobium.Journal of microbiology (Seoul, Korea) · 2022Article
- Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells.Scientific reports · 2017Article
- iTAP: integrated transcriptomics and phenotype database for stress response of Escherichia coli and Saccharomyces cerevisiae.BMC research notes · 2015Article
- ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae.PloS one · 2015Article
- Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions.BMC systems biology · 2015Article
- Molecular mechanisms of system responses to novel stimuli are predictable from public data.Nucleic acids research · 2014Article
- Physiological and biochemical responses of Yarrowia lipolytica to dehydration induced by air-drying and freezing.PloS one · 2014Article
- Towards decrypting cryptobiosis--analyzing anhydrobiosis in the tardigrade Milnesium tardigradum using transcriptome sequencing.PloS one · 2014Article
- Identification of genes potentially involved in solute stress response in Sphingomonas wittichii RW1 by transposon mutant recovery.Frontiers in microbiology · 2014Article
- Role of trehalose in heat and desiccation tolerance in the soil bacterium Rhizobium etli.BMC microbiology · 2012Article
- Pathway correlation profile of gene-gene co-expression for identifying pathway perturbation.PloS one · 2012Article
- Contribution of transcription factor binding site motif variants to condition-specific gene expression patterns in budding yeast.PloS one · 2012Article
- A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.PloS one · 2012Article
- Connecting the dots between PubMed abstracts.PloS one · 2012Article
- Article
- A multi-level study of recombinant Pichia pastoris in different oxygen conditions.BMC systems biology · 2010Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A transcriptional analysis of the response of Saccharomyces cerevisiae strain BY4743 to controlled air-drying (desiccation) and subsequent rehydration under minimal glucose conditions was performed. Expression of genes involved in fatty acid oxidation and the glyoxylate cycle was observed to increase during drying and remained in this state during the rehydration phase. When the BY4743 expression profile for the dried sample was compared to that of a commercially prepared dry active yeast, strikingly similar expression changes were observed. The fact that these two samples, dried by different means, possessed very similar transcriptional profiles supports the hypothesis that the response to desiccation is a coordinated event independent of the particular conditions involved in water removal. Similarities between "stationary-phase-essential genes" and those upregulated during desiccation were also noted, suggesting commonalities in different routes to reduced metabolic states. Trends in extracellular and intracellular glucose and trehalose levels suggested that the cells were in a "holding pattern" during the rehydration phase, a concept that was reinforced by cell cycle analyses. Application of a "redescription mining" algorithm suggested that sulfur metabolism is important for cell survival during desiccation and rehydration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.