ArticleApplied and environmental microbiology2005
Cooccurrence of ScDSP gene expression, cell death, and DNA fragmentation in a marine diatom, Skeletonema costatum.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Diatoms exhibit dynamic chloroplast calcium signals in response to high light and oxidative stress.Plant physiology · 2024Article
- Differential Expression of Stress Adaptation Genes in a DiatomInternational journal of molecular sciences · 2024Article
- Structural Identification of Metalloproteomes in Marine Diatoms, an Efficient Algae Model in Toxic Metals Bioremediation.Molecules (Basel, Switzerland) · 2022Article
- Quantitative Proteomic Analysis Reveals Novel Insights into Intracellular Silicate Stress-Responsive Mechanisms in the DiatomInternational journal of molecular sciences · 2019Article
- Autoinhibitory sterol sulfates mediate programmed cell death in a bloom-forming marine diatom.Nature communications · 2017Article
- Article
- Cellular responses associated with ROS production and cell fate decision in early stress response to iron limitation in the diatom Thalassiosira pseudonana.Journal of proteome research · 2014Article
- The effect of polyunsaturated aldehydes on Skeletonema marinoi (Bacillariophyceae): the involvement of reactive oxygen species and nitric oxide.Marine drugs · 2014Article
- Death-specific protein in a marine diatom regulates photosynthetic responses to iron and light availability.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Identification and characterization of an extracellular alkaline phosphatase in the marine diatom Phaeodactylum tricornutum.Marine biotechnology (New York, N.Y.) · 2013Article
- Quantification of diatom gene expression in the sea by selecting uniformly transcribed mRNA as the basis for normalization.Applied and environmental microbiology · 2012Article
- Distribution patterns and phylogeny of marine stramenopiles in the north pacific ocean.Applied and environmental microbiology · 2012Article
- N-glycans of Phaeodactylum tricornutum diatom and functional characterization of its N-acetylglucosaminyltransferase I enzyme.The Journal of biological chemistry · 2011Article
- Nitric oxide as a signaling factor to upregulate the death-specific protein in a marine diatom, Skeletonema costatum, during blockage of electron flow in photosynthesis.Applied and environmental microbiology · 2008Article
- Iron starvation and culture age activate metacaspases and programmed cell death in the marine diatom Thalassiosira pseudonana.Eukaryotic cell · 2008Article
- The identification of three novel genes involved in the rapid-growth regulation in a marine diatom, Skeletonema costatum.Marine biotechnology (New York, N.Y.)Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel death-specific gene, ScDSP, was obtained from a death stage subtraction cDNA library of the diatom Skeletonema costatum. The full length of ScDSP cDNA was 921 bp in length, containing a 699-bp open reading frame encoding 232 amino acids and two stretches of 66 and 156 bp in the 5' and 3' untranslated regions, respectively. Analysis of the peptide structure revealed that ScDSP contained a signal peptide domain, a transmembrane domain, and a pair of EF-hand motifs. When S. costatum grew exponentially at a rate of 1.3 day(-1), the ScDSP mRNA level was at 2 mumol . mole 18S rRNA(-1). In contrast, when the culture entered the death phase with a growth rate decreasing to 0.5 day(-1), ScDSP mRNA increased dramatically to 668 mumol . mole 18S rRNA(-1), and a high degree of DNA fragmentation was simultaneously observed. Under the influence of a light-dark cycle, ScDSP expression in both exponential and stationary phases clearly showed a diel rhythm, but the daily mean mRNA level was significantly higher in the stationary phase. Our results suggest that ScDSP may play a role in the molecular mechanism of self-destructive autolysis in phytoplankton under stress.
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