ArticlePlanta2006
The maize heat shock factor-binding protein paralogs EMP2 and HSBP2 interact non-redundantly with specific heat shock factors.
Article in Planta, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Adaptive response to long-term high temperatures during the reproductive development in Arabidopsis thaliana.Planta · 2026Article
- Elucidating the patterns of pleiotropy and its biological relevance in maize.PLoS genetics · 2023Article
- Heat shock factor binding proteinFrontiers in plant science · 2023Article
- Regulatory Mechanisms of Heat Stress Response and Thermomorphogenesis in Plants.Plants (Basel, Switzerland) · 2022Review
- Response of Tomato (Plants (Basel, Switzerland) · 2022Article
- Article
- GFDP: the gene family database in poplar.Database : the journal of biological databases and curation · 2018Article
- Transcriptomic analysis to uncover genes affecting cold resistance in the Chinese honey bee (Apis cerana cerana).PloS one · 2017Article
- MGFD: the maize gene families database.Database : the journal of biological databases and curation · 2016Article
- Novel isoforms of heat shock transcription factor 1, HSF1γα and HSF1γβ, regulate chaperone protein gene transcription.The Journal of biological chemistry · 2014Article
- Identification of heat shock factor binding protein in Plasmodium falciparum.Malaria journal · 2014Article
- An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development.Developmental biology · 2014Article
- Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development.Plant physiology · 2013Article
- Genetic variations of HSBP1 gene and its effect on thermal performance traits in Chinese Holstein cattle.Molecular biology reports · 2013Article
- A low molecular weight proteome comparison of fertile and male sterile 8 anthers of Zea mays.Plant biotechnology journal · 2012Article
- Characterisation of hookworm heat shock factor binding protein (HSB-1) during heat shock and larval activation.International journal for parasitology · 2011Article
- Genome-wide identification, classification and analysis of heat shock transcription factor family in maize.BMC genomics · 2011Article
- AtHSBP functions in seed development and the motif is required for subcellular localization and interaction with AtHSFs.Plant signaling & behavior · 2010Article
- Cytosol-localized heat shock factor-binding protein, AtHSBP, functions as a negative regulator of heat shock response by translocation to the nucleus and is required for seed development in Arabidopsis.Plant physiology · 2010Article
- Identification and expression analysis of OsHsfs in rice.Journal of Zhejiang University. Science. B · 2009Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The heat shock response (HSR) is a conserved mechanism by which transcripts of heat shock protein (hsp) genes accumulate following mobilization of heat shock transcription factors (HSFs) in response to thermal stress. Studies in animals identified the heat shock factor-binding protein1 (HSBP1) that interacts with heat shock transcription factor1 (HSF1) during heat shock attenuation; overexpression analyses revealed that the coiled-coil protein HSBP1 functions as a negative regulator of the HSR. Zea mays contains two HSBP paralogs, EMP2 and HSBP2, which exhibit differential accumulation during the HSR and plant development. Embryo-lethal recessive emp2 mutations revealed that EMP2 is required for the down-regulation of hsp transcription during embryogenesis, whereas accumulation of HSBP2 is induced in seedlings following heat shock. Notwithstanding, no interaction has yet been demonstrated between a plant HSBP and a plant HSF. In this report 22 maize HSF isoforms are identified comprising three structural classes: HSF-A, HSF-B and HSF-C. Phylogenetic analysis of Arabidopsis, maize and rice HSFs reveals that at least nine ancestral HSF isoforms were present prior to the separation of monocot and eudicots, followed by differential amplification of HSF members in these lineages. Yeast two-hybrid analyses show that EMP2 and HSBP2 interact non-redundantly with specific HSF-A isoforms. Site-specific mutagenesis of HSBP2 reveals that interactions between hydrophobic residues within the coiled coil are required for HSF::HSBP2 binding; domain swapping demonstrate that the isoform specificity of HSF::HSBP interaction is conferred by residues outside of the coiled coil. These data suggest that the non-redundant functions of the maize HSBPs may be explained, at least in part, by the specificity of HSBP::HSF interactions during plant development.
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