ArticleThe Journal of cell biology2005
Dendritic BC1 RNA in translational control mechanisms.
Article in The Journal of cell biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 71 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 138 citations in OpenAlex.
- Reading the SINEs - functionality in noncoding RNA 'cheap genes'.RNA biology · 2026Review
- RNA-RNA interactions coordinate GABA metabolism and signaling.bioRxiv : the preprint server for biology · 2025Article
- Autoimmune RNA dysregulation and seizures: therapeutic prospects in neuropsychiatric lupus.Life science alliance · 2022Article
- Article
- Long Noncoding RNA SCIRT Promotes HUVEC Angiogenesis via Stabilizing VEGFA mRNA Induced by Hypoxia.Oxidative medicine and cellular longevity · 2022Article
- ncRNA BC1 influences translation in the oocyte.RNA biology · 2021Article
- The Role of LncRNAs in Translation.Non-coding RNA · 2021Review
- Human Long Noncoding RNA Interactome: Detection, Characterization and Function.International journal of molecular sciences · 2020Review
- Long Noncoding RNAs, New Critical Regulators in Cancer Immunity.Frontiers in oncology · 2020Review
- Identification of Long Non-Coding RNA Expression Profiles and Co-Expression Genes in Thyroid Carcinoma Based on The Cancer Genome Atlas (TCGA) Database.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Neuronal BC RNA Transport Impairments Caused by Systemic Lupus Erythematosus Autoantibodies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- The Role of Non-Coding RNA in Congenital Heart Diseases.Journal of cardiovascular development and disease · 2019Review
- Regulatory BC200 RNA in peripheral blood of patients with invasive breast cancer.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2018Article
- BC200 (BCYRN1) - The shortest, long, non-coding RNA associated with cancer.Non-coding RNA research · 2018Review
- The Expression Alteration of BC1 RNA and its Interaction with Eukaryotic Translation Initiation Factor eIF4A Post-Status Epilepticus.Neurochemical research · 2018Article
- Expression of BC1 Impairs Spatial Learning and Memory in Alzheimer's Disease Via APP Translation.Molecular neurobiology · 2018Article
- Brain cytoplasmic RNA 1 suppresses smooth muscle differentiation and vascular development in mice.The Journal of biological chemistry · 2018Article
- The Role of Long Noncoding RNAs in Central Nervous System and Neurodegenerative Diseases.Frontiers in behavioral neuroscience · 2018Review
- The role of long non-coding RNAs in cardiac development and disease.AIMS genetics · 2018Review
- Effects of regulatory BC1 RNA deletion on synaptic plasticity, learning, and memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2017Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Translational control at the synapse is thought to be a key determinant of neuronal plasticity. How is such control implemented? We report that small untranslated BC1 RNA is a specific effector of translational control both in vitro and in vivo. BC1 RNA, expressed in neurons and germ cells, inhibits a rate-limiting step in the assembly of translation initiation complexes. A translational repression element is contained within the unique 3' domain of BC1 RNA. Interactions of this domain with eukaryotic initiation factor 4A and poly(A) binding protein mediate repression, indicating that the 3' BC1 domain targets a functional interaction between these factors. In contrast, interactions of BC1 RNA with the fragile X mental retardation protein could not be documented. Thus, BC1 RNA modulates translation-dependent processes in neurons and germs cells by directly interacting with translation initiation factors.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.