ArticlePhotosynthesis research2004
From chloroplasts to chaperones: how one thing led to another.
Article in Photosynthesis research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Expression, Purification, and Preliminary Protection Study of Dehydrin PicW1 From the Biomass ofFrontiers in bioengineering and biotechnology · 2022Article
- From chaperonins to Rubisco assembly and metabolic repair.Protein science : a publication of the Protein Society · 2017Review
- Vallabhaneni Sita Rama Das, 1933-2010: teacher and mentor.Photosynthesis research · 2016Article
- The K-segments of the wheat dehydrin DHN-5 are essential for the protection of lactate dehydrogenase and β-glucosidase activities in vitro.Molecular biotechnology · 2013Article
- Assembly chaperones: a perspective.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- Plant dehydrins and stress tolerance: versatile proteins for complex mechanisms.Plant signaling & behavior · 2011Review
- Cpn20: siamese twins of the chaperonin world.Plant molecular biology · 2009Review
- The continuing conundrum of the LEA proteins.Die Naturwissenschaften · 2007Review
- Discoveries in Rubisco (Ribulose 1,5-bisphosphate carboxylase/oxygenase): a historical perspective.Photosynthesis research · 2007Article
- LEA proteins prevent protein aggregation due to water stress.The Biochemical journal · 2005Article
- Discoveries in oxygenic photosynthesis (1727-2003): a perspective.Photosynthesis research · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two lessons I have learned during my research career are the importance of following up unexpected observations and realizing that the most obvious interpretation of such observations can be rational but wrong. When you carry out an experiment there is usually an expectation that the result will fall within a range of predictable outcomes, and it is natural to feel pleased when this turns out to be the case. In my view this response is a mistake. What you should be hoping for is a puzzling result that was not anticipated since with persistence and luck further experiments may uncover something new. In this article I give a personal account of how studies of the synthesis of proteins by isolated intact chloroplasts from pea leaves eventually led to the discovery of the chaperonins and the formulation of the general concept of the molecular chaperone function that is now seen to be a fundamental aspect of how all cells work.
Identifiers
16328830What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.