ArticlePhotosynthesis research2004
Characterization of Arabidopsis Mutants for the Variable Subunit of Ferredoxin:thioredoxin Reductase.
Article in Photosynthesis research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Natural variation in ZmDapF1 enhances maize drought resilience.Nature plants · 2025Article
- A Semi-throughput Procedure for Assaying Plant NADP-malate Dehydrogenase Activity Using a Plate Reader.Bio-protocol · 2023Article
- Insight into morphological and molecular variations across Iranian spinach landraces.Molecular biology reports · 2021Article
- Efficient Photosynthetic Functioning ofFrontiers in plant science · 2020Article
- Chloroplast thioredoxin systems dynamically regulate photosynthesis in plants.The Biochemical journal · 2019Review
- Chloroplast Redox Regulatory Mechanisms in Plant Adaptation to Light and Darkness.Frontiers in plant science · 2019Review
- Reactive Oxygen Species and the Redox-Regulatory Network in Cold Stress Acclimation.Antioxidants (Basel, Switzerland) · 2018Review
- Article
- Two distinct redox cascades cooperatively regulate chloroplast functions and sustain plant viability.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Involvement of Iron-Containing Proteins in Genome Integrity in Arabidopsis Thaliana.Genome integrity · 2015Review
- The redox-sensitive chloroplast trehalose-6-phosphate phosphatase AtTPPD regulates salt stress tolerance.Antioxidants & redox signaling · 2014Article
- Putative role of the malate valve enzyme NADP-malate dehydrogenase in H2O2 signalling in Arabidopsis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Article
- Overexpression of plastidial thioredoxins f and m differentially alters photosynthetic activity and response to oxidative stress in tobacco plants.Frontiers in plant science · 2013Article
- Single cystathionine β-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis.The Plant cell · 2011Article
- Inactivation of thioredoxin reductases reveals a complex interplay between thioredoxin and glutathione pathways in Arabidopsis development.The Plant cell · 2007Article
- Thioredoxins in chloroplasts.Current genetics · 2007Review
- Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.The Plant cell · 2006Article
- A complete ferredoxin/thioredoxin system regulates fundamental processes in amyloplasts.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Thioredoxins in Arabidopsis and other plants.Photosynthesis research · 2005Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ferredoxin/thioredoxin reductase (FTR) is the key enzyme of a light dependent redox regulatory system controlling enzyme activities in oxygenic photosynthetic cells. It is composed of two dissimilar subunits. The catalytic subunit contains a [4Fe-4S] cluster and a redox-active disulfide bridge as the active site. The function of the second subunit, named the variable subunit because it has less conserved primary sequence and length, is not yet known. In order to get insights into the physiological role and importance of FTR, we studied two Arabidopsis mutant lines in which one of two genes encoding FTRA subunit was disrupted by T-DNA insertion. In FTRA1 mutants, the absence of the corresponding transcript was not compensated by the increase in the level of FTRA2 mRNA. Mutant plants exhibited phenotypic perturbations when compared with wild-type plants. Disruptants were found significantly more sensitive to oxidative stress as imposed under high light or in the presence of paraquat. Mutants were further characterized at the biochemical level. Despite the fact that no difference was found by immunodetection of FTR polypeptides, evidence for an impaired FTR system occurring in the mutants was obtained by measuring the endogenous activation rate of one of its targets. In the leaves of mutants placed under normal culture conditions, NADP-dependent malate dehydrogenase (NADP-MDH) activation rate was abnormally low. A partially compensating increase of the enzyme activity was found as well as a higher amount of 2-cys-peroxiredoxin. Our results provide in planta confirmation of the antioxidant role previously proposed for some of the plastidial thioredoxins from Arabidopsis thaliana. The variable subunit of the FTR proved to be important, but its precise role remains to be established.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.