ArticleThe Plant cell2006
ROR1/RPA2A, a putative replication protein A2, functions in epigenetic gene silencing and in regulation of meristem development in Arabidopsis.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 63 citations in OpenAlex.
- Genome-wide identification and characterization of the RPA gene family in maize.BMC plant biology · 2026Article
- Downregulation of RORl via STAT3 and P300 Promotes P38 Pathway- Dependent Lens Epithelial Cells Apoptosis in Age-Related Cataract.Biochemical genetics · 2026Article
- Regulatory dynamics of gene expression in the developing male gametophyte of Arabidopsis.Plant reproduction · 2023Article
- Linkage mapping and QTL analysis of flowering time in faba bean.Scientific reports · 2021Article
- Review
- Article
- Structural Aspects of DNA Repair and Recombination in Crop Improvement.Frontiers in genetics · 2020Review
- A conserved but plant-specific CDK-mediated regulation of DNA replication protein A2 in the precise control of stomatal terminal division.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Peroxisomal β-oxidation regulates histone acetylation and DNA methylation inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- METHIONINE ADENOSYLTRANSFERASE4 Mediates DNA and Histone Methylation.Plant physiology · 2018Article
- IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis.The Plant cell · 2017Article
- Requirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis.The Plant journal : for cell and molecular biology · 2016Article
- The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation.Plant physiology · 2016Article
- Methyl-CpG-binding domain protein MBD7 is required for active DNA demethylation in Arabidopsis.Plant physiology · 2015Article
- Regulation of active DNA demethylation by an α-crystallin domain protein in Arabidopsis.Molecular cell · 2014Article
- Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication.Nucleic acids research · 2014Article
- Folate polyglutamylation is involved in chromatin silencing by maintaining global DNA methylation and histone H3K9 dimethylation in Arabidopsis.The Plant cell · 2013Article
- Comparative transcriptome analysis and marker development of two closely related Primrose species (Primula poissonii and Primula wilsonii).BMC genomics · 2013Article
- DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana.Frontiers in plant science · 2013Article
- Regulating DNA replication in plants.Cold Spring Harbor perspectives in biology · 2012Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We screened for suppressors of repressor of silencing1 (ros1) using the silenced 35S promoter-neomycin phosphotransferase II (Pro(35S):NPTII) gene as a marker and identified two allelic mutants, ror1-1 and ror1-2 (for suppressor of ros1). Map-based cloning revealed that ROR1 encodes a 31-kD protein similar to DNA replication protein A2 (RPA2A). Mutations in ROR1 reactivate the silenced Pro(35S):NPTII gene but not RD29A promoter-luciferase in the ros1 mutant. DNA methylation in rDNA, centromeric DNA, and RD29A promoter regions is not affected by ror1. However, chromatin immunoprecipitation data suggest that histone H3 acetylation is increased and histone H3K9 dimethylation is decreased in the 35S promoter in the ror1 ros1 mutant compared with ros1. These results indicate that release of silenced Pro(35S):NPTII by ror1 mutations is independent of DNA methylation. ROR1/RPA2A is strongly expressed in shoot and root meristems. Mutations in ROR1/RPA2A affect cell division in meristems but not final cell sizes. Our work suggests important roles of ROR1/RPA2A in epigenetic gene silencing and in the regulation of plant development.
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