ArticleThe Plant cell2006
The temperature-dependent change in methylation of the Antirrhinum transposon Tam3 is controlled by the activity of its transposase.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Review
- Epigenomics in stress tolerance of plants under the climate change.Molecular biology reports · 2023Review
- Article
- Regulatory mechanism ofFrontiers in plant science · 2023Article
- Transposable Element Tissue-Specific Response to Temperature Stress in the Stenothermal FishAnimals : an open access journal from MDPI · 2022Article
- Article
- Temporal changes in transcripts of miniature inverted-repeat transposable elements during rice endosperm development.The Plant journal : for cell and molecular biology · 2022Article
- Epigenetic variation: A major player in facilitating plant fitness under changing environmental conditions.Frontiers in cell and developmental biology · 2022Review
- Reprogramming of theFrontiers in plant science · 2022Article
- Exploration of Epigenetics for Improvement of Drought and Other Stress Resistance in Crops: A Review.Plants (Basel, Switzerland) · 2021Review
- Herbicide stress-induced DNA methylation changes in two Zea mays inbred lines differing in Roundup® resistance.Journal of applied genetics · 2021Article
- Changes in DNA Methylation inFrontiers in plant science · 2021Article
- A chromosome-scale reference genome of trifoliate orange (Poncirus trifoliata) provides insights into disease resistance, cold tolerance and genome evolution in Citrus.The Plant journal : for cell and molecular biology · 2020Article
- Genome-Wide Analysis Reveals Dynamic Epigenomic Differences in Soybean Response to Low-Phosphorus Stress.International journal of molecular sciences · 2020Article
- RNA directed DNA methylation and seed plant genome evolution.Plant cell reports · 2020Review
- Greenhouse Spatial Effects Detected in the Barley (Frontiers in plant science · 2020Article
- Transgenerational activation of an autonomous DNA transposon, Dart1-24, by 5-azaC treatment in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Activation of transposable elements and genetic instability during long-term culture of the human fungal pathogen Candida albicans.Biogerontology · 2019Article
- Transposable element insertions in fission yeast drive adaptation to environmental stress.Genome research · 2019Article
- Chilling-induced DNA Demethylation is associated with the cold tolerance of Hevea brasiliensis.BMC plant biology · 2018Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Antirrhinum majus transposon Tam3 undergoes low temperature-dependent transposition (LTDT). Growth at 15 degrees C permits transposition, whereas growth at 25 degrees C strongly suppresses it. The degree of Tam3 DNA methylation is altered somatically and positively correlated with growth temperature, an exceptional epigenetic system in plants. Using a Tam3-inactive line, we show that methylation change depends on Tam3 activity. Random binding site selection analysis and electrophoretic mobility shift assays revealed that the Tam3 transposase (TPase) binds to the major repeat in the subterminal regions of Tam3, the site showing the biggest temperature-dependent change in methylation state. Methylcytosines in the motif impair the binding ability of the TPase. Proteins in a nuclear extract from plants grown at 15 degrees C but not 25 degrees C bind to this motif in Tam3. The decrease in Tam3 DNA methylation at low temperature also requires cell division. Thus, TPase binding to Tam3 occurs only during growth at low temperature and immediately after DNA replication, resulting in a Tam3-specific decrease in methylation of transposon DNA. Consequently, the Tam3 methylation level in LTDT is regulated by Tam3 activity, which is dependent on the ability of its TPase to bind DNA and affected by growth temperature. Thus, the methylation/demethylation of Tam3 is the consequence, not the cause, of LTDT.
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