ArticleAtencion primaria2005
[Substitution of generic for brand medicines in primary care. Factors associated to refuse the change].
Article in Atencion primaria, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Reply to 'Patient experience of the transition from Xalatan to generic latanoprost'.Eye (London, England) · 2014Article
- Evaluating patients' perceptions regarding generic medicines in Jordan.Journal of pharmaceutical policy and practice · 2013Article
- Physicians' and patients' opinions on the use of generic drugs.Journal of pharmacology & pharmacotherapeutics · 2012Article
- [Acceptance of replacement by generic medicines at community pharmacies].Atencion primaria · 2007Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn Spain prescription of generic drugs is still low. We have attempted first to estimate the proportion of patients who switch from brand-name medication to generics once properly informed, and secondly to determine the variables associated with the resistance to make this switch.
designCross-sectional study.
settingPrimary care.
participantsWe ask to participate in our study to 360 family doctors, each of them should choose the first 5 patients who take prescribed drugs with generic alternatives. 110 doctors refuse and 48 had incomplete or illegible information. Finally 202 doctors and 1006 patients formed our sample. Main measurements. We estimated the percentage of non acceptance and also the variables associated by bivariate analysis and logistic regression.
results13% (11%-15%) of patients were unwilling to switch to generic medicine. Variables associated with non acceptance were old age, having a low educational level and being "retired" --which means not having to pay for drugs. The non acceptance was also higher if the patient did not know what a generic drug was, had never taken a generic drug before, and the doctor that originally prescribed the medicine was a hospital specialist. The two characteristics independently associated to non acceptance were the fact that the patient ignored what a generic drug was (odds ratio [OR]=4,0; 95% CI, 2,6-6,4), and the fact hat the doctor that originally prescribed the drug was not the family doctor but a hospital one (OR=3,7; 95% CI, 2,3-5,8).
conclusionsThe percentage of patients that did not accept switching to generic drugs is very low. To increase the substitution for generics we need to better inform and educate the population and to increase the use of generics in the hospital setting.
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