Evidence map›Paper›PMID 16323101›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2006

Parasitic central nervous system infections in immunocompromised hosts: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis.

Melanie Walker, James G Kublin, Joseph R Zunt

Open access · greenAbstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 89 citations in OpenAlex.

  1. Review
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  15. NeuroAIDS in the Asia Pacific Region.Journal of neurovirology · 2008
    Article
  16. Review
  17. Fever of unknown origin due to zoonoses.Infectious disease clinics of North America · 2007
    Review
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Melanie WalkerDepartment of Neurology, University of Washington School of Medicine, Seattle, Washington, USA.
James G Kublin
Joseph R Zunt
University of Washington · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZA

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Grace C. John-Stewart · 1988 to 2026
$104.9M
Central Nervous System Infections in PeruR21NS048838 · NINDS · UNIVERSITY OF WASHINGTON · PI ZUNT, JOSEPH RAYMOND · 2003 to 2004
$286k
NIAID NIH HHS AI27757NIAID NIH HHS P30 AI027757NINDS NIH HHS R21 NS048838NINDS NIH HHS R21 NS48838
6 · The paper itself

Abstract

Immunosuppression associated with HIV infection or following transplantation increases susceptibility to central nervous system (CNS) infections. Because of increasing international travel, parasites that were previously limited to tropical regions pose an increasing infectious threat to populations at risk for acquiring opportunistic infection, especially people with HIV infection or individuals who have received a solid organ or bone marrow transplant. Although long-term immunosuppression caused by medications such as prednisone likely also increases the risk for acquiring infection and for developing CNS manifestations, little published information is available to support this hypothesis. In an earlier article published in Clinical Infectious Diseases, we described the neurologic manifestations of some of the more common parasitic CNS infections. This review will discuss the presentation, diagnosis, and treatment of the following additional parasitic CNS infections: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis.

Indexed as

Immunocompromised HostBrain DiseasesCentral Nervous System Parasitic InfectionsHumansLeishmaniasisMalaria, CerebralMicrosporidiosisTrypanosomiasis, African

Identifiers

PMID16323101
PMCPMC2683841
OpenAlexW1977149007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.