Evidence map›Paper›PMID 16322809›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2005

Natural health products, modulation of immune function and prevention of chronic diseases.

Pierre S Haddad, Georges A Azar, Simon Groom, Michel Boivin

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
12.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.

  1. Multidisciplinary rehabilitation treatments for patients with fibromyalgia: a systematic review.European journal of physical and rehabilitation medicine · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Food & nutrition research · 2023
    Article
  6. The therapeutic mechanism ofFrontiers in veterinary science · 2023
    Article
  7. Review
  8. Immune-Enhancing Effects of Co-treatment WithFrontiers in nutrition · 2022
    Article
  9. Article
  10. Wild epiphytic Bangladeshi orchidsJournal of advanced veterinary and animal research · 2021
    Article
  11. Bioactivity-Guided Extract Optimization ofPlants (Basel, Switzerland) · 2021
    Article
  12. Immunomodulatory Effects of Green Tea Polyphenols.Molecules (Basel, Switzerland) · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Immunostimulatory Effect ofEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Pierre S HaddadFondation Lucie et André Chagnon, 2001 McGill College, Suite 1000, Montreal, Quebec, Canada. pierre.haddad@umontreal.ca
Georges A Azar
Simon Groom
Michel Boivin
Cegep Edouard Montpetit · CACentre Hospitalier de l’Université de Montréal · CAMcGill University · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system is increasingly found to be involved in the development of several chronic illnesses, for which allopathic medicine has provided limited tools for treatment and especially prevention. In that context, it appears worthwhile to target the immune system in order to modulate the risk of certain chronic illnesses. Meanwhile, natural health products (NHPs) are generating renewed interest, particularly in the prevention and treatment of several chronic diseases. Over 20 scientists from fields related to immune function and NHPs were thus convened to establish the state of knowledge on these subjects and to explore future research directions. This review summarizes the result of discussions held during the symposium. It thus seeks to be thought provoking rather than to comprehensively cover such broad areas of research. Notably, a brief overview of the immune system is presented, including potentially useful targets and strategies to keep it in an equilibrated state, in order to prevent certain disorders. The pertinence and limitations of targeting the immune system to prevent chronic diseases is also discussed. The paper then discusses the usefulness and limitations of current experimental tools available to study the immune modulating effects of NHPs. Finally, a concise review of some of the most studied NHPs showing promising immunomodulatory activity is given, and avenues for future research are described.

Identifiers

PMID16322809
PMCPMC1297498
OpenAlexW2142477983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.