Evidence map›Paper›PMID 16322510›Full record

ArticleGenetics2006

Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli.

Lisa Lukas, Andrei Kuzminov

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Synthetic lethal mutants inJournal of bacteriology · 2023
    Pooled it
  2. Article
  3. Comment on "A commensal strain ofScience advances · 2019
    Article
  4. Replication Fork Breakage and Restart in Escherichia coli.Microbiology and molecular biology reviews : MMBR · 2018
    Review
  5. Article
  6. Article
  7. Article
  8. Iron and zinc binding activity of Escherichia coli topoisomerase I homolog YrdD.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2014
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase.Acta crystallographica. Section F, Structural biology and crystallization communications · 2006
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa LukasDepartment of Microbiology, University of Illinois, Urbana, Illinois 61801, USA.
Andrei Kuzminov
University of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rdgB mutants depend on recombinational repair of double-strand breaks. To assess other consequences of rdgB inactivation in Escherichia coli, we isolated RdgB-dependent mutants. All transposon inserts making cells dependent on RdgB inactivate genes of double-strand break repair, indicating that chromosomal fragmentation is the major consequence of RdgB inactivation.

Indexed as

Gene SilencingMutationChromosomes, BacterialDNA, BacterialDNA DamageDNA RepairEscherichia coliEscherichia coli ProteinsPurinesPyrimidinesPyrophosphatasesDNA, BacterialEscherichia coli ProteinsPurinesPyrimidinesPyrophosphatasesRdgB protein, E coli

Identifiers

PMID16322510
PMCPMC1456232
OpenAlexW2161531737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.