ArticleJournal of bacteriology2005
L-Canavanine made by Medicago sativa interferes with quorum sensing in Sinorhizobium meliloti.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 132 citations in OpenAlex.
- You Talking to Me? Quorum Sensing in Symbiotic Microbes and Their Response to Environmental Variation.Microorganisms · 2026Review
- Quorum sensing in bacteria: insights into communication and inhibition strategies-a review.Archives of microbiology · 2026Review
- Quorum Signaling Molecules: Interactions Between Plants and Associated Pathogens.International journal of molecular sciences · 2025Review
- Role of bacterial quorum sensing in plant growth promotion.World journal of microbiology & biotechnology · 2024Review
- Advancing Antibiotic-Resistant Microbe Combat: Nanocarrier-Based Systems in Combination Therapy Targeting Quorum Sensing.Pharmaceutics · 2024Review
- Soybean-mediated suppression of BjaI/BjaRApplied and environmental microbiology · 2024Article
- Phytopathogenic bacteria utilize host glucose as a signal to stimulate virulence through LuxR homologues.Molecular plant pathology · 2023Article
- Antibacterial and Antibiofilm Effects of Allelopathic Compounds Identified inMolecules (Basel, Switzerland) · 2023Article
- The Importance of Microorganisms for Sustainable Agriculture-A Review.Metabolites · 2022Review
- Canavanine utilizationRSC chemical biology · 2022Article
- Protocol: a simple method for biosensor visualization of bacterial quorum sensing and quorum quenching interaction on Medicago roots.Plant methods · 2022Article
- Host Plant Species Influences the Composition of Milkweed and Monarch Microbiomes.Frontiers in microbiology · 2022Article
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- BIOFILM: FORMATION AND NATURAL PRODUCTS' APPROACH TO CONTROL - A REVIEW.African journal of infectious diseases · 2022Article
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- Article
- Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression.Journal, genetic engineering & biotechnology · 2018Review
- Regulation Mediated by N-Acyl Homoserine Lactone Quorum Sensing Signals in the Rhizobium-Legume Symbiosis.Genes · 2018Review
- Water-Soluble Humic Materials Regulate Quorum Sensing inFrontiers in microbiology · 2018Article
- Microbial interactions: ecology in a molecular perspective.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sinorhizobium meliloti is a gram-negative soil bacterium, capable of establishing a nitrogen-fixing symbiosis with its legume host, alfalfa (Medicago sativa). Quorum sensing plays a crucial role in this symbiosis, where it influences the nodulation process and the synthesis of the symbiotically important exopolysaccharide II (EPS II). S. meliloti has three quorum-sensing systems (Sin, Tra, and Mel) that use N-acyl homoserine lactones as their quorum-sensing signal molecule. Increasing evidence indicates that certain eukaryotic hosts involved in symbiotic or pathogenic relationships with gram-negative bacteria produce quorum-sensing-interfering (QSI) compounds that can cross-communicate with the bacterial quorum-sensing system. Our studies of alfalfa seed exudates suggested the presence of multiple signal molecules capable of interfering with quorum-sensing-regulated gene expression in different bacterial strains. In this work, we choose one of these QSI molecules (SWI) for further characterization. SWI inhibited violacein production, a phenotype that is regulated by quorum sensing in Chromobacterium violaceum. In addition, this signal molecule also inhibits the expression of the S. meliloti exp genes, responsible for the production of EPS II, a quorum-sensing-regulated phenotype. We identified this molecule as l-canavanine, an arginine analog, produced in large quantities by alfalfa and other legumes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.