Evidence map›Paper›PMID 16320091›Full record

Trial reportMagma (New York, N.Y.)2005

Dynamic interleaved 1H/31P STEAM MRS at 3 Tesla using a pneumatic force-controlled plantar flexion exercise rig.

M Meyerspeer, M Krssák, G J Kemp, M Roden, E Moser

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Magma (New York, N.Y.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

  1. Dynamic multivoxel-localizedNMR in biomedicine · 2018
    Trial
  2. Trial
  3. Heme arginate improves reperfusion patterns after ischemia: a randomized, placebo-controlled trial in healthy male subjects.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2012
    Trial
  4. Effect of ischemic preconditioning in skeletal muscle measured by functional magnetic resonance imaging and spectroscopy: a randomized crossover trial.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011
    Trial
  5. A Novel 9-ChannelMagnetic resonance in medicine · 2026
    Article
  6. NMR in biomedicine · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. InterleavedMagnetic resonance in medicine · 2020
    Article
  11. MR compatible ergometers for dynamicJournal of applied biomedicine · 2019
    Review
  12. In-vivoAnalytical biochemistry · 2017
    Review
  13. Article
  14. Interleaved multivoxelMagnetic resonance in medicine · 2017
    Article
  15. DynamicNMR in biomedicine · 2016
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

M MeyerspeerMR Centre of Excellence, Medical University of Vienna, Lazarettgasse 14, A-1090 Vienna, Austria.
M Krssák
G J Kemp
M Roden
E Moser
Medical University of Vienna · ATHanusch Hospital · ATUniversity of Liverpool · GB

Funding

Austrian Science Fund FWF L 36
6 · The paper itself

Abstract

objectiveTo develop a measurement method for interleaved acquisition of 1H and 31 STEAM localised spectra of exercising human calf muscle. MATERIALS AND

methodsA non-magnetic exercise rig with a pneumatic piston and sensors for force and pedal angle was constructed to enable plantar flexion measured in the 3 T MR scanner, which holds the dual tuned (1H ,31P) surface coil used for signal transmission and reception.

results(31) spectra acquired in interleaved mode benefit from higher Signal to noise ratio (factor of 1.34 +/-0.06 for PCr) compared to standard acquisition due to the Nuclear Overhauser effect and substantial PCr/P(i) changes during exercise can be observed in 31P spectra. 1H spectral quality is equal to that in single mode experiments and allows Cr2 changes to be monitored.

conclusionThe feasibility of dynamic interleaved localised 1H and 31P spectroscopy during plantar flexion exercise has been demonstrated using a custom-built pneumatic system for muscle activation. This opens the possibility of studying the dynamics of metabolism with multi nuclear MRS in a single run.

Indexed as

AdultEquipment DesignEquipment Failure AnalysisExercise TestFemaleHumansMagnetic Resonance SpectroscopyMaleMuscle ContractionMuscle, SkeletalMyoglobinPhosphatesPressureMyoglobinPhosphates

Identifiers

PMID16320091
PMCPMC4876922
OpenAlexW2041010655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.