Evidence map›Paper›PMID 16318687›Full record

ArticleEmerging infectious diseases2005

Antimicrobial drug resistance: "Prediction is very difficult, especially about the future".

Patrice Courvalin

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. eMIC-AntiKP: Estimating minimum inhibitory concentrations of antibiotics towardsComputational and structural biotechnology journal · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Novel Bacteriophages in Enterococcus spp.Current microbiology · 2010
    Article
  18. Article
  19. The determinants of the antibiotic resistance process.Infection and drug resistance · 2009
    Article
  20. Global challenge of multidrug-resistant Acinetobacter baumannii.Antimicrobial agents and chemotherapy · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Patrice CourvalinUnité des Agents Antibactériens, Institut Pasteur, Paris, France. pcourval@pasteur.fr

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolution of bacteria towards resistance to antimicrobial drugs, including multidrug resistance, is unavoidable because it represents a particular aspect of the general evolution of bacteria that is unstoppable. Therefore, the only means of dealing with this situation is to delay the emergence and subsequent dissemination of resistant bacteria or resistance genes. Resistance to antimicrobial drugs in bacteria can result from mutations in housekeeping structural or regulatory genes. Alternatively, resistance can result from the horizontal acquisition of foreign genetic information. The 2 phenomena are not mutually exclusive and can be associated in the emergence and more efficient spread of resistance. This review discusses the predictable future of the relationship between antimicrobial drugs and bacteria.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacteriaBacterial ProteinsForecastingGene Transfer, HorizontalHumansMicrobial Sensitivity TestsMutationAnti-Bacterial AgentsBacterial Proteins

Identifiers

PMID16318687
PMCPMC3366764

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.