ReviewBritish journal of cancer2006
The measurement and therapeutic implications of circulating tumour cells in breast cancer.
Review in British journal of cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02123862 (Cultured Circulating Tumor Cells - Development of a Novel Platform for Drug Discovery and in Vitro Chemosensitivity Testing in Prostate and Other Cancers), which is not on this map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cultured Circulating Tumor Cells - Development of a Novel Platform for Drug Discovery and in Vitro Chemosensitivity Testing in Prostate and Other Cancers
Who cites it
39 citing papers in PubMed.
- Review
- Microfluidics for the Isolation and Detection of Circulating Tumor Cells.Advances in experimental medicine and biology · 2022Article
- Capture and selective release of multiple types of circulating tumor cells using smart DNAzyme probes.Chemical science · 2020Article
- Association of urinary and plasma DNA in early breast cancer patients and its links to disease relapse.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018Article
- Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.Scientific reports · 2017Article
- Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Article
- The Significance of Epithelial-to-Mesenchymal Transition for Circulating Tumor Cells.International journal of molecular sciences · 2016Review
- Review: circulating tumor cells in the practice of breast cancer oncology.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2016Review
- Real-Time qPCR-Based Detection of Circulating Tumor Cells from Blood Samples of Adjuvant Breast Cancer Patients: A Preliminary Study.Breast care (Basel, Switzerland) · 2016Article
- Circulating tumor cells in germ cell tumors: are those biomarkers of real prognostic value? A review.Clujul medical (1957) · 2016Review
- Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics.Nature protocols · 2016Article
- Short-term expansion of breast circulating cancer cells predicts response to anti-cancer therapy.Oncotarget · 2015Article
- Isolation of viable cancer cells in antibody-functionalized microfluidic devices.Biomicrofluidics · 2014Article
- Simple Multi-level Microchannel Fabrication by Pseudo-Grayscale Backside Diffused Light Lithography.RSC advances · 2013Article
- Breast cancer metastasis: issues for the personalization of its prevention and treatment.The American journal of pathology · 2013Review
- Detection of Circulating Tumour Cells from Blood of Breast Cancer Patients via RT-qPCR.Cancers · 2013Article
- Detection of circulating tumour cells on mRNA levels with established breast cancer cell lines.Biomedical reports · 2013Article
- Microneedle Biosensor: A Method for Direct Label-free Real Time Protein Detection.Sensors and actuators. B, Chemical · 2013Article
- Detection of tumor cell-specific mRNA in the peripheral blood of patients with breast cancer—evaluation of several markers with real-time reverse transcription-PCR.International journal of molecular sciences · 2013Article
- Separation of tumor cells with dielectrophoresis-based microfluidic chip.Biomicrofluidics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circulating tumours cells (CTCs) represent an important biologic link in the spread of breast cancer from primary to metastatic disease. CTCs are strong predictors of prognosis in patients with metastatic breast cancer. Research to date has focused on development of methods with adequate sensitivity and specificity to reproducibly identify these rare events. Future research will focus on the biologic phenotypes of these cells with goals to understand mechanisms of metastasis, to identify novel therapeutic targets, and to monitor response to therapy.
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Registered trials
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