ReviewCurrent diabetes reports2005
Theories concerning the pathogenesis of the acute charcot foot suggest future therapy.
Review in Current diabetes reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 60 citations in OpenAlex.
- Trial
- RANKL-RANK-OPG Pathway in Charcot Diabetic Foot: Pathophysiology and Clinical-Therapeutic Implications.International journal of molecular sciences · 2023Review
- Therapeutics of Charcot neuroarthropathy and pharmacological mechanisms: A bone metabolism perspective.Frontiers in pharmacology · 2023Review
- Delayed Diagnosis of Bilateral Neuroarthropathy: Serious Impact on the Development of Charcot's Foot, a Case Report.Medicina (Kaunas, Lithuania) · 2022Article
- Trends in the relation between hyperglycemia correction and active Charcot neuroarthropathy: results from the EPICHAR study.BMJ open diabetes research & care · 2022Article
- Impact of the Rapid Normalization of Chronic Hyperglycemia on the Receptor Activator of Nuclear Factor-Kappa B Ligand and the Osteoprotegerin System in Patients Living with Type 2 Diabetes: RANKL-GLYC Study.Medicina (Kaunas, Lithuania) · 2022Article
- Fracture of the Bone Inducing Its Necrosis as the End Point in the Evolution of Untreated Neuroarthropathy.Medicina (Kaunas, Lithuania) · 2021Article
- Why the Risk of Developing Neuroarthropathy Is Higher After Simultaneous Kidney and Pancreatic Transplantation Compared to Kidney Transplantation Only: The Role of Euglycemia.Annals of transplantation · 2021Article
- An overview of Charcot's neuroarthropathy.Journal of clinical & translational endocrinology · 2020Review
- Prevalence of polymorphisms in OPG, RANKL and RANK as potential markers for Charcot arthropathy development.Scientific reports · 2017Article
- Neuropathic osteoarthropathy with and without superimposed osteomyelitis in patients with a diabetic foot.Skeletal radiology · 2016Review
- [Tibiotalocalcaneal corrective arthrodesis in Charcot arthropathy of the ankle with a retrograde nail].Operative Orthopadie und Traumatologie · 2015Article
- Charcot foot and ankle with osteomyelitis.Diabetic foot & ankle · 2013Review
- Etiology, pathophysiology and classifications of the diabetic Charcot foot.Diabetic foot & ankle · 2013Article
- Charcot osteoarthropathy in diabetes: A brief review with an emphasis on clinical practice.World journal of diabetes · 2011Article
- An overview of conservative treatment options for diabetic Charcot foot neuroarthropathy.Diabetic foot & ankle · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acute Charcot foot is characterized by bone fracture and dislocation, and is a rare complication of distal symmetrical neuropathy in diabetes. The cause is unknown, but it cannot be attributed solely to loss of protective sensation. However, recent advances in understanding the mechanisms of osteoclast activation have suggested that the key abnormality may lie in an enhanced inflammatory response to injury, which is itself linked to increased bone lysis. The recognition that the acute Charcot foot is essentially an inflammatory arthropathy suggests new options for the management of this potentially devastating condition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.