ArticleWorld journal of surgery2005
Gender differences in quality of life of patients with rectal cancer. A five-year prospective study.
Article in World journal of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Conversations for providers caring for patients with rectal cancer: Comparison of long-term patient-centered outcomes for patients with low rectal cancer facing ostomy or sphincter-sparing surgery.CA: a cancer journal for clinicians · 2016Pooled it
- Quality of life after rectal resection for cancer, with or without permanent colostomy.The Cochrane database of systematic reviews · 2012Pooled it
- Psychological interventions for the sexual sequelae of cancer: a review of the literature.Journal of cancer survivorship : research and practice · 2010Pooled it
- Does gender influence outcomes from a multidisciplinary intervention for quality of life designed for patients with advanced cancer?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Trial
- Sexual Satisfaction in Psycho-Oncology Patients: Characteristics and Correlates.Psychiatry investigation · 2026Article
- Ten-Year Outcomes in Colorectal Cancer-Competing Risks and Patient Vulnerability: A Prospective Multicenter Observational Study.Journal of clinical medicine · 2026Article
- Sex differences in health-related quality of life and psychological distress among colorectal cancer patients: a 2-year longitudinal study.Journal of cancer survivorship : research and practice · 2025Observational
- Lack of precision in the reporting of sex and gender in cancer clinical trials with a PRO endpoint: an exploratory literature review.BMC medical research methodology · 2025Review
- Social determinants of health, diet, and symptom experiences in colorectal cancer survivors: A scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Cancer-Specificity of Sex Differences and Sex-Specific Impact of Sociodemographic Characteristics in Cancer Patients' Health-Related Quality of Life: A Cross-Sectional Study.Psycho-oncology · 2025Article
- Sex-related differences in postoperative patient-reported outcomes among lung cancer patients: a multicenter cohort study.BMC cancer · 2025Observational
- The bowel function instrument for rectal cancer survivors with anastomosis and ostomy.Journal of psychosomatic research · 2024Article
- Shared Decision-Making, Sphincter Preservation, and Rectal Cancer Treatment: Identifying and Executing What Matters Most to Patients.Clinics in colon and rectal surgery · 2024Review
- Article
- Quality of life in Tunisian colorectal cancer patients: a cross-sectional study.Journal of cancer research and clinical oncology · 2023Article
- Quality of Life after Rectal Cancer Resection Comparing Anterior Resection, Abdominoperineal Resection, and Complicated Cases.Visceral medicine · 2022Article
- What happens to cancer survivors attending a structured cancer survivorship clinic? Symptoms, quality of life and lifestyle changes over the first year at the Sydney Cancer Survivorship Centre clinic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- When do defecation function and quality of life recover for patients with non-ostomy and ostomy surgery of rectal cancer?BMC surgery · 2020Article
- Gender differences in health-related quality of life among patients with colorectal cancer.Journal of gastrointestinal oncology · 2019Article
- Is WHODAS 2.0 Useful for Colorectal Cancer Survivors?Annals of rehabilitation medicine · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine how quality of life changes over time and to assess gender-related differences in quality of life of rectal cancer patients we conducted a 5-year study. Little is known about how quality of life (QoL) changes over time in patients after surgery for rectal cancer, and whether gender of the patients is associated with a different perception of QoL. The aim of this study was to assess prospectively, changes in quality of life after surgery for rectal cancer, with a focus on gender related differences. Over a 5-year period, the EORTC-QLQ-C-30 and a tumor-specific module were prospectively administered to patients before surgery, at discharge, 3, 6, 12, and 24 months postoperatively. Comparisons were made between female and male patients. A total of 519 patients participated in the study, 264 men and 255 women. The two groups were comparable in terms of surgical procedures, adjuvant treatment, tumor stage, and histology. Most QoL scores dropped significantly below baseline in the early postoperative period. From the third month onward, global health, emotional and physical functioning, improved. Female gender was associated with significantly worse global health and physical functioning and with higher scores on treatment strain and fatigue. Men reported difficulties with sexual enjoyment; furthermore, over time, sexual problems created high levels of strain in men, worse than baseline levels in the early postoperative period. These problems tended to continue over the course of time. The findings in this study confirm that QoL changes after surgery and differs between men and women. Women appear to be affected by impaired physical functioning and global health. Female gender is associated with significantly higher fatigue levels and increased strain values after surgery. Through impaired sexual enjoyment, men are put more under strain than woman.
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Registered trials
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