Evidence map›Paper›PMID 16310431›Full record

ArticleThe American journal of cardiology2005

Relation of low socioeconomic status to C-reactive protein in patients with coronary heart disease (from the heart and soul study).

Lindsey A Lubbock, Anne Goh, Sadia Ali, James Ritchie, Mary A Whooley

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in The American journal of cardiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Income and recurrent events after a coronary event in women.European journal of epidemiology · 2008
    Trial
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  13. The social patterns of a biological risk factor for disease: race, gender, socioeconomic position, and C-reactive protein.The journals of gerontology. Series B, Psychological sciences and social sciences · 2012
    Article
  14. Low-dose nonlinear effects of smoking on coronary heart disease risk.Dose-response : a publication of International Hormesis Society · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lindsey A LubbockDepartment of Veterans Affairs Medical Center, San Francisco, California, USA.
Anne Goh
Sadia Ali
James Ritchie
Mary A Whooley

Funding

Epidemiology of Depression and Heart Failure in AgingR01HL079235 · NHLBI · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WHOOLEY, MARY A · 2005 to 2009
$4.2M
NHLBI NIH HHS R01 HL079235
6 · The paper itself

Abstract

Low socioeconomic status (SES) is associated with poor health outcomes in patients who have coronary heart disease (CHD). Inflammation is a potential mechanism by which low SES may lead to adverse cardiovascular outcomes, but it is not known whether low SES is associated with inflammation in patients who have CHD. We measured high-sensitivity C-reactive protein (CRP) levels in a cross-sectional study of 985 adults who had CHD. Income and education were determined by self-report. We used ordinal logistic regression to examine the association of income and education with CRP. Of the 985 participants, 390 had high CRP levels (>3 mg/dl). The proportion of participants who had high CRP levels ranged from 30% (103 of 340) in those who had a college degree to 51% (65 of 127) in those who had less than a high school degree (p<0.0001). The proportion of subjects who had a high CRP level ranged from 28% (52 of 183) in those who had annual income>or=$50,000 to 42% (199 of 974) in those who had an annual income<$20,000 (p<0.001). After adjustment for traditional cardiovascular risk factors and other potential confounding variables, lower income and education remained associated with higher CRP levels. In conclusion, low SES is associated with high CRP levels in patients who have CHD. This observation raises the possibility that inflammation may contribute to the adverse cardiovascular outcomes associated with low SES.

Indexed as

Educational StatusIncomeSocial ClassAgedCaliforniaConfounding Factors, EpidemiologicCoronary DiseaseC-Reactive ProteinFemaleFollow-Up StudiesHealth Status IndicatorsHumansMaleProspective StudiesRisk FactorsSocioeconomic FactorsC-Reactive Protein

Identifiers

PMID16310431
PMCPMC2776677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.