ArticleBritish journal of sports medicine2005
Effects of dietary carbohydrate on delayed onset muscle soreness and reactive oxygen species after contraction induced muscle damage.
Article in British journal of sports medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 54 citations in OpenAlex.
- Carbohydrate supplementation delays DNA damage in elite runners during intensive microcycle training.European journal of applied physiology · 2012Trial
- Piezo2-Initiated Ultrafast Signaling and Its Acquired Channelopathy in Light of Quantum Gravity Theory.International journal of molecular sciences · 2026Review
- Heart Rate Variability Alterations During Delayed-Onset Muscle Soreness-Inducing Exercise-With Piezo2 Interpretation.Sports (Basel, Switzerland) · 2025Article
- Sitting Less, Recovering Faster: Investigating the Relationship between Daily Sitting Time and Muscle Recovery following Intense Exercise: A Pilot Study.Journal of functional morphology and kinesiology · 2024Article
- Exercise-Induced Muscle Damage and Protein Intake: A Bibliometric and Visual Analysis.Nutrients · 2022Review
- The Comparative Effect of Different Timings of Whole Body Cryotherapy Treatment With Cold Water Immersion for Post-Exercise Recovery.Frontiers in sports and active living · 2022Article
- The Effects of Age and Body Fat Content on Post-Downhill Run Recovery Following Whole Body Cryotherapy.International journal of environmental research and public health · 2021Article
- Downhill Running: What Are The Effects and How Can We Adapt? A Narrative Review.Sports medicine (Auckland, N.Z.) · 2020Review
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- Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin.BBA clinical · 2016Article
- Effect of ThermaCare HeatWraps and Icy Hot Cream/Patches on Skin and Quadriceps Muscle Temperature and Blood Flow.Journal of chiropractic medicine · 2016Article
- Supplementation with a polyphenolic blend improves post-exercise strength recovery and muscle soreness.Food & nutrition research · 2015Article
- Review
- Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle.Journal of applied physiology (Bethesda, Md. : 1985) · 2011Review
- Pilot study on the effect of grounding on delayed-onset muscle soreness.Journal of alternative and complementary medicine (New York, N.Y.) · 2010Article
- Cell damage, antioxidant status, and cortisol levels related to nutrition in ski mountaineering during a two-day race.Journal of sports science & medicine · 2010Article
- The prevention and treatment of exercise-induced muscle damage.Sports medicine (Auckland, N.Z.) · 2008Review
- The effect of muscle-damaging exercise on blood and skeletal muscle oxidative stress: magnitude and time-course considerations.Sports medicine (Auckland, N.Z.) · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDelayed onset muscle soreness (DOMS) occurs after unaccustomed exercise and has been suggested to be attributable to reactive oxygen species (ROS). Previous studies have shown increased ROS after lengthening contractions, attributable to invading phagocytes. Plasma glucose is a vital fuel for phagocytes, therefore carbohydrate (CHO) status before exercise may influence ROS production and DOMS.
objectiveTo examine the effect of pre-exercise CHO status on DOMS, ROS production, and muscle function after contraction induced muscle damage.
methodTwelve subjects performed two downhill runs, one after a high CHO diet and one after a low CHO diet. Blood samples were drawn for analysis of malondialdehyde, total glutathione, creatine kinase, non-esterified fatty acids, lactate, glucose, and leucocytes. DOMS and muscle function were assessed daily.
resultsThe high CHO diet resulted in higher respiratory exchange ratio and lactate concentrations than the low CHO diet before exercise. The low CHO diet resulted in higher non-esterified fatty acid concentrations before exercise. DOMS developed after exercise and remained for up to 96 hours, after both diets. A biphasic response in creatine kinase occurred after both diets at 24 and 96 hours after exercise. Malondialdehyde had increased 72 hours after exercise after both diets, and muscle function was attenuated up to this time.
conclusionsDownhill running resulted in increased ROS production and ratings of DOMS and secondary increases in muscle damage. CHO status before exercise had no effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.