ReviewCancer investigation2005
Nucleolar adaptation in human cancer.
Review in Cancer investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 86 citations in OpenAlex.
- Beyond the Ribosome: The Expanding Role of the Nucleolus in Neurodegenerative Pathways.Molecular neurobiology · 2026Review
- HTLV-I Basic Leucine Zipper Factor (sHBZ) Actively Associates with Nucleophosmin (B23) in the Nucleolus.Viruses · 2025Article
- Identification of curcumin as a novel natural inhibitor of rDNA transcription.Cell cycle (Georgetown, Tex.) · 2020Article
- The Nucleolus: In Genome Maintenance and Repair.International journal of molecular sciences · 2017Review
- Article
- Up-regulation of ribosome biogenesis by MIR196A2 genetic variation promotes endometriosis development and progression.Oncotarget · 2016Article
- Nucleolus-derived mediators in oncogenic stress response and activation of p53-dependent pathways.Histochemistry and cell biology · 2016Review
- Article
- Human Ribosomal RNA-Derived Resident MicroRNAs as the Transmitter of Information upon the Cytoplasmic Cancer Stress.BioMed research international · 2016Article
- Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus.Journal of cellular biochemistry · 2016Article
- Nucleolar dominance and maternal control of 45S rDNA expression.Proceedings. Biological sciences · 2015Article
- Coexpression Pattern Analysis of NPM1-Associated Genes in Chronic Myelogenous Leukemia.BioMed research international · 2015Article
- Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia.Cellular and molecular life sciences : CMLS · 2014Article
- A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli.Molecular biology of the cell · 2014Article
- Induced expression of nucleolin phosphorylation-deficient mutant confers dominant-negative effect on cell proliferation.PloS one · 2014Article
- Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus.Molecular biology of the cell · 2013Article
- P19ARF and RasV¹² offer opposing regulation of DHX33 translation to dictate tumor cell fate.Molecular and cellular biology · 2013Article
- Identification of novel markers that demarcate the nucleolus during severe stress and chemotherapeutic treatment.PloS one · 2013Article
- Recent progress in histochemistry and cell biology.Histochemistry and cell biology · 2012Review
- Identification of DHX33 as a mediator of rRNA synthesis and cell growth.Molecular and cellular biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
While the nucleolus was first observed over two hundred years ago, its role in human cancers is only now being appreciated. Long thought to be a static, ribosome-producing, subnuclear organelle, recent investigations have shown a more dynamic and adaptable side of the nucleolus. Containing not only proteins for the production of ribosomes but also newfound nucleolar oncogenes and tumor suppressors, mechanistic links between the nucleolus and cancer are now more evident. In this regard, much of the work from the past decade has focused on the ability of these proteins to promote and suppress tumorigenesis from the nucleolus. In this review, we will discuss how historical measurements of the nucleolus are being translated into contemporary studies of nucleolar dysfunction in human cancer.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.