ArticleBritish journal of clinical pharmacology2005
Dramatic change in prescribing of hormone replacement therapy in The Netherlands after publication of the Million Women Study: a follow-up study.
Article in British journal of clinical pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Drug Safety Issues Covered by Lay Media: A Cohort Study of Direct Healthcare Provider Communications Sent between 2001 and 2015 in The Netherlands.Drug safety · 2020Article
- Effectiveness of and overdiagnosis from mammography screening in the Netherlands: population based study.BMJ (Clinical research ed.) · 2017Article
- Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening.Climacteric : the journal of the International Menopause Society · 2017Article
- Article
- Is transdermal menopausal hormone therapy a safer option than oral therapy?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Postmenopausal hormone therapy and breast cancer risk: current status and unanswered questions.Endocrinology and metabolism clinics of North America · 2011Review
- Current and emerging therapies for the treatment of osteoporosis.Journal of experimental pharmacology · 2010Review
- Why do stress and urge incontinence co-occur much more often than expected?International urogynecology journal and pelvic floor dysfunction · 2008Review
- Exogenous and endogenous hormones and breast cancer.Best practice & research. Clinical endocrinology & metabolism · 2008Review
- Differences in menopausal hormone therapy use among women in Germany between 1998 and 2003.BMC women's health · 2007Article
- SERMs for the treatment and prevention of breast cancer.Reviews in endocrine & metabolic disorders · 2007Review
- Prescribing of hormone therapy for menopause, tibolone, and bisphosphonates in women in the UK between 1991 and 2005.European journal of clinical pharmacology · 2007Article
- Gender differences in colorectal cancer: implications for age at initiation of screening.British journal of cancer · 2007Article
- Recent Trends in Breast Cancer Incidence and Mortality in Germany.Breast care (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo estimate the diffusion of new safety information concerning postmenopausal hormonal replacement therapy (HRT) into prescribing practice in The Netherlands and to assess the impact of revised guidelines on the long-term treatment of HRT.
designCross-sectional study.
settingCommunity pharmacy dispensing data from a population of approximately 450,000 patients in the northern and eastern part of The Netherlands. POPULATION: Women aged 45-69 years to whom at least one HRT prescription was dispensed between 1 January 2000 and 1 January 2004.
main outcome measuresAnnual and quarter prevalences of HRT and the proportion of new HRT users, switchers and continuous HRT users per quarter.
resultsThe prevalence of HRT prescribing decreased significantly from 107/1000 [95% confidence interval (CI) 104, 110] in 2000 to 87/1000 (95% CI 84, 89) in 2003. The decreasing prevalence was especially evident among the younger age groups and was most pronounced among users of oestrogen/progestagen combinations. The publication of the Women Health Initiative Study (WHI) was followed by a modest decrease in prescribing of HRT, whereas prescribing of HRT declined dramatically after publication of the Million Women Study (MWS) in August 2003. Among the continuous HRT users in the 4th quarter of 2002, 55% used HRT longer than 3 years. This percentage was 53 in the 4th quarter of 2003.
conclusionsIn contrast to the release of the WHI study results, publication of the MWS was followed by a dramatic fall in prescribing of HRT in The Netherlands. Despite the new recommendation that long-term HRT use should be discouraged, the proportion of long-term users did not change after the publication of the MWS.
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