Evidence map›Paper›PMID 16304187›Full record

ArticleAntimicrobial agents and chemotherapy2005

Caspofungin and liposomal amphotericin B therapy of experimental murine scedosporiosis.

Rosie Bocanegra, Laura K Najvar, Steve Hernandez, Dora I McCarthy, John R Graybill

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Infections caused by Scedosporium spp.Clinical microbiology reviews · 2008
    Review
  4. Successful Treatment ofAllergy & rhinology (Providence, R.I.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rosie BocanegraThe University of Texas Health Science Center at San Antonio, Department of Medicine/Division of Infectious Diseases (MC 7881), 7703 Floyd Curl Drive, San Antonio, Texas 78229-3900, USA. Bocanegra@uthscsa.edu
Laura K Najvar
Steve Hernandez
Dora I McCarthy
John R Graybill

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunosuppressed mice were infected intravenously with conidia of Scedosporium prolificans. Treatment was begun 1 day later with liposomal amphotericin B, caspofungin, or both drugs initiated concurrently. Amphotericin B and caspofungin were each effective, but combined therapy did not appear to offer advantages over liposomal amphotericin B alone.

Indexed as

ScedosporiumAmphotericin BAnimalsAntifungal AgentsCaspofunginDose-Response Relationship, DrugDrug InteractionsDrug Therapy, CombinationEchinocandinsLipopeptidesMiceMycetomaPeptides, CyclicAmphotericin BAntifungal AgentsCaspofunginEchinocandinsLipopeptidesliposomal amphotericin BPeptides, Cyclic

Identifiers

PMID16304187
PMCPMC1315953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.