Evidence map›Paper›PMID 16299348›Full record

ArticleInfection and immunity2005

Azurin of pathogenic Neisseria spp. is involved in defense against hydrogen peroxide and survival within cervical epithelial cells.

Hsing-Ju Wu, Kate L Seib, Jennifer L Edwards, Michael A Apicella, Alastair G McEwan, Michael P Jennings

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
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  8. Review
  9. Lipid-Modified Azurin ofFrontiers in microbiology · 2018
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hsing-Ju WuThe School of Molecular and Microbial Sciences, The University of Queensland, Brisbane 4072, Australia.
Kate L Seib
Jennifer L Edwards
Michael A Apicella
Alastair G McEwan
Michael P Jennings
University of Queensland · AUUniversity of Iowa · US

Funding

THE ROLE OF CHLAMYDIA TRACHOMATIS IN ENDOMETRIAL CAUSES OF INFERTILITYU19AI038515 · NIAID · BOSTON MEDICAL CENTER · PI WETZLER, LEE MARK · 1995 to 2003
$4.3M
THE BIOLOGY OF PATHOGENIC NEISSERIAR01AI045728 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 1999 to 2010
$3.7M
NIAID NIH HHS AI38515NIAID NIH HHS AI43294NIAID NIH HHS AI45728NIAID NIH HHS R01 AI045728NIAID NIH HHS U19 AI038515
6 · The paper itself

Abstract

Laz, a lipid-modified azurin of the human pathogens Neisseria gonorrhoeae and Neisseria meningitidis, is involved in defense against oxidative stress and copper toxicity; laz mutant strains are hypersensitive to hydrogen peroxide and copper. The N. gonorrhoeae laz mutant also has decreased survival in an ex vivo primary human ectocervical epithelial assay.

Indexed as

Drug Resistance, BacterialAzurinCells, CulturedCervix UteriCopperEpithelial CellsFemaleHumansHydrogen PeroxideMutationNeisseria gonorrhoeaeNeisseria meningitidisOxidative StressAzurinCopperHydrogen Peroxide

Identifiers

PMID16299348
PMCPMC1307039
OpenAlexW2013932696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.