ArticlePlant physiology2005
The alternative oxidase of plant mitochondria is involved in the acclimation of shoot growth at low temperature. A study of Arabidopsis AOX1a transgenic plants.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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74 citing papers in PubMed, 205 citations in OpenAlex.
- Essential mitochondrial activity in Physcomitrium patens relies on complementary cytochrome and alternative oxidase pathways.The Plant journal : for cell and molecular biology · 2026Article
- Mitochondrial Reactive Oxygen Species in Infection and Immunity.Biomolecules · 2024Review
- Roles of mitochondrial alternative oxidase in photosynthetic electron transport in illuminated leaves ofJournal of biosciences · 2024Article
- Systems biology of plant metabolic interactions.Journal of biosciences · 2024Review
- Effects of OsAOX1a Deficiency on Mitochondrial Metabolism at Critical Node of Seed Viability in Rice.Plants (Basel, Switzerland) · 2023Article
- Metabolism and Signaling of Plant Mitochondria in Adaptation to Environmental Stresses.International journal of molecular sciences · 2022Review
- The Genome-Wide Identification of Long Non-Coding RNAs Involved in Floral Thermogenesis inInternational journal of molecular sciences · 2022Article
- Alternative oxidase (AOX) 1a and 1d limit proline-induced oxidative stress and aid salinity recovery in Arabidopsis.Plant physiology · 2022Article
- Overexpression of GhKTI12 Enhances Seed Yield and Biomass Production in Nicotiana Tabacum.Genes · 2022Article
- Distinct responses of growth and respiration to growth temperatures in two mangrove species.Annals of botany · 2022Article
- Altering the balance between AOX1A and NDB2 expression affects a common set of transcripts in Arabidopsis.Frontiers in plant science · 2022Article
- Establishing an efficient protoplast transient expression system for investigation of floral thermogenesis in aroids.Plant cell reports · 2022Article
- CarrotPlants (Basel, Switzerland) · 2021Article
- Theoretical analysis of a temperature-dependent model of respiratory OThe New phytologist · 2021Article
- Alternative Oxidase Inhibition Impairs Tobacco Root Development and Root Hair Formation.Frontiers in plant science · 2021Article
- Complementation of ROS scavenging secondary metabolites with enzymatic antioxidant defense system augments redox-regulation property under salinity stress in rice.Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- A multiscale approach to detect selection in nonmodel tree species: Widespread adaptation despite population decline inEvolutionary applications · 2020Article
- Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function?Mitochondrion · 2019Article
- Overexpression ofG3 (Bethesda, Md.) · 2019Article
- AtNDB2 Is the Main External NADH Dehydrogenase in Mitochondria and Is Important for Tolerance to Environmental Stress.Plant physiology · 2019Article
14 more citing papers are in PubMed but not listed here.
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The alternative oxidase (AOX) pathway of plant mitochondria uncouples respiration from mitochondrial ATP production and may ameliorate plant performance under stressful environmental conditions, such as cold temperatures, by preventing excess accumulation of reactive oxygen species. We tested this model in whole tissues by growing AtAOX1a-transformed Arabidopsis (Arabidopsis thaliana) plants at 12 degrees C. For the first time, to our knowledge, in plants genetically engineered for AOX, we identified a vegetative shoot growth phenotype. Compared with wild type at day 21 after sowing, anti-sense and overexpressing lines showed, on average, 27% reduced leaf area and 25% smaller rosettes versus 30% increased leaf area and 33% larger rosette size, respectively. Lines overexpressing a mutated, constitutively active AOX1a showed smaller phenotypic effects. These phenotypic differences were not the result of a major alteration of the tissue redox state because the changes in levels of lipid peroxidation products, reflecting oxidative damage, and the expression of genes encoding antioxidant and electron transfer chain redox enzymes did not correspond with the shoot phenotypes. However, the observed phenotypes were correlated with the amount of total shoot anthocyanin at low temperature and with the transcription of the flavonoid pathway genes PAL1 and CHS. These results demonstrate that (1) AOX activity plays a role in shoot acclimation to low temperature in Arabidopsis, and that (2) AOX not only functions to prevent excess reactive oxygen species formation in whole tissues under stressful environmental conditions but also affects metabolism through more pervasive effects, including some that are extramitochondrial.
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