ReviewJournal of neuro-oncology2006
Primitive neuroectodermal tumours (PNETs) located in the spinal canal; the relevance of classification as central or peripheral PNET : case report of a primary spinal PNET occurrence with a critical literature review.
Review in Journal of neuro-oncology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 55 citations in OpenAlex.
- Metastatic thoracic and lumbar intramedullary and extramedullary Ewing's sarcoma: a rare case report and literature review.The Journal of international medical research · 2022Review
- A case of giant Ewing's sarcoma (EES)/primitive neuroectodermal tumor (PNET) of the cervicothoracic junction in children with incomplete paralysis of both lower limbs: Case report and literature review.Frontiers in surgery · 2022Article
- Cervical intramedullary recurrent Ewing sarcoma after 10-year disease-free survival in an adult: a case report and review of literature.Spinal cord series and cases · 2021Review
- Primitive neuroectodermal tumor of the cervix diagnosed during pregnancy: a rare case report with discussion.BMC pregnancy and childbirth · 2021Article
- Primitive neuroectodermal tumor of urinary bladder: A case report and literature review.Medicine · 2020Review
- Primary adult primitive neuroectodermal tumor of the bladder: A case report and literature review.Medicine · 2020Article
- Primitive Neuroectodermal Tumour Invading the Inferior Vena Cava.European journal of case reports in internal medicine · 2020Article
- Treatment Outcomes and Prognostic Factors of Patients With Primary Spinal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumors.Frontiers in oncology · 2019Article
- Cervicomedullary primitive neuroectodermal tumor of the spine: Case report.Surgical neurology international · 2018Article
- Primary intramedullary primitive neuroectodermal tumor: A case report and review of the literature.Medicine · 2017Article
- Peripheral facial palsy, the only presentation of a primitive neuroectodermal tumor of the skull base.International journal of surgery case reports · 2016Article
- Clinical presentation and long-term outcome of primary spinal peripheral primitive neuroectodermal tumors.Journal of neuro-oncology · 2015Article
- Primitive neuroectodermal tumor in the spinal canal: A case report.Oncology letters · 2015Article
- A Unique Case of Primary Ewing's Sarcoma of the Cervical Spine in a 53-Year-Old Male: A Case Report and Review of the Literature.Case reports in medicine · 2015Article
- Peripheral primitive neuroectodermal tumor of the dura in a 51-year-old woman following intensive treatment for breast cancer.The American journal of case reports · 2014Article
- Intracranial metastasis from primary spinal primitive neuroectodermal tumor.Asian journal of neurosurgery · 2013Article
- Primary spinal extradural Ewing's sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature.Surgical neurology international · 2012Article
- Primary spinal intramedullary primitive neuroectodermal tumor.Journal of pediatric neurosciences · 2012Article
- The evaluation of CD99 immunoreactivity and EWS/FLI1 translocation by fluorescence in situ hybridization in central PNETs and Ewing's sarcoma family of tumors.Pathology oncology research : POR · 2011Article
- Primary central nervous system primitive neuroectodermal tumors (CNS-PNETs) of the spinal cord in children: four cases from the German HIT database with a critical review of the literature.Journal of neuro-oncology · 2011Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraspinal location of central PNET (cPNET) is very rare. We present a case, critically review all publications of primary intraspinal cPNET occurrence and discuss tendencies in clinical presentation. In several previous attempts to summarise, authors often confused cPNET with peripheral PNET (pPNET). cPNET and pPNET are different entities with different immunohistochemical profiles and genetic backgrounds. Clinically, they are both aggressive tumours, but exhibit different characteristics in their local manifestation and metastatic spread. Survival rates are quite similar provided that treatment is applied according to the established protocols. Protocols in cPNET treatment differ from those for pPNET as regards the order of the treatment sub-modalities, specific chemotherapeutic regimen and intensity, radiation dose and its extent and consequently, the side effects. Therefore, failure to distinguish cPNET from pPNET leads to clinical guidance and treatment proposals based on false assumptions, which might effect outcomes. Often, distinguishing between cPNET and pPNET is easy, because they occur in different location. In the case of intraspinal tumour location, however, the differentiation is crucial because both primary cPNET and pPNET can occur intraspinally, even though this is rare. Nowadays, demonstrating the expression of MIC2 glycoprotein by immunocytochemical staining (CD99) showing the specific EWS-FLI1 chimeric gene presence in pPNET, offers an easy way of making a differential diagnosis between cPNET and pPNET.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.