ArticleJournal of bacteriology2005
Four unusual two-component signal transduction homologs, RedC to RedF, are necessary for timely development in Myxococcus xanthus.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 28 citations in OpenAlex.
- Multiple communication mechanisms between sensor kinases are crucial for virulence in Pseudomonas aeruginosa.Nature communications · 2018Article
- Chemosensory regulation of a HEAT-repeat protein couples aggregation and sporulation in Myxococcus xanthus.Journal of bacteriology · 2014Article
- Pattern-formation mechanisms in motility mutants of Myxococcus xanthus.Interface focus · 2012Article
- The genetic organisation of prokaryotic two-component system signalling pathways.BMC genomics · 2010Article
- A novel "four-component" two-component signal transduction mechanism regulates developmental progression in Myxococcus xanthus.The Journal of biological chemistry · 2009Article
- Upward mobility and alternative lifestyles: a report from the 10th biennial meeting on Bacterial Locomotion and Signal Transduction.Molecular microbiology · 2009Article
- The atypical hybrid histidine protein kinase RodK in Myxococcus xanthus: spatial proximity supersedes kinetic preference in phosphotransfer reactions.Journal of bacteriology · 2009Article
- Bacterial development in the fast lane.Journal of bacteriology · 2008Article
- EspA, an orphan hybrid histidine protein kinase, regulates the timing of expression of key developmental proteins of Myxococcus xanthus.Journal of bacteriology · 2008Article
- Bioinformatics and experimental analysis of proteins of two-component systems in Myxococcus xanthus.Journal of bacteriology · 2008Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
We identified a cluster of four two-component signal transduction genes that are necessary for proper progression of Myxococcus xanthus through development. redC to redF mutants developed and sporulated early, resulting in small, numerous, and disorganized fruiting bodies. Yeast two-hybrid analyses suggest that RedCDEF act in a single signaling pathway. The previously identified espA gene displays a phenotype similar to that of redCDEF. However, combined mutants defective in espA redCDEF exhibited a striking additive developmental phenotype, suggesting that EspA and RedC to RedF play independent roles in controlling developmental progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.