ArticleJournal of bacteriology2005
sinI- and expR-dependent quorum sensing in Sinorhizobium meliloti.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 92 citations in OpenAlex.
- Quorum Signaling Molecules: Interactions Between Plants and Associated Pathogens.International journal of molecular sciences · 2025Review
- Quorum Sensing: Not Just a Bridge Between Bacteria.MicrobiologyOpen · 2025Review
- Article
- Scent of a Symbiont: The Personalized Genetic Relationships of Rhizobium-Plant Interaction.International journal of molecular sciences · 2022Review
- The Presence of Plant-Associated Bacteria Alters Responses toPlants (Basel, Switzerland) · 2020Article
- Deciphering the Symbiotic Significance of Quorum Sensing Systems ofMicroorganisms · 2020Article
- Quorum Quenching Activity of the PGPRFrontiers in microbiology · 2020Article
- Use of Plasmid pVMG to Make Transcriptional ß-Glucuronidase Reporter Gene Fusions in theBiological procedures online · 2019Article
- Regulation Mediated by N-Acyl Homoserine Lactone Quorum Sensing Signals in the Rhizobium-Legume Symbiosis.Genes · 2018Review
- Detection of New Quorum SensingFrontiers in microbiology · 2018Article
- A Family of Single Copy repABC-Type Shuttle Vectors Stably Maintained in the Alpha-Proteobacterium Sinorhizobium meliloti.ACS synthetic biology · 2017Article
- Large Diversity and Original Structures of Acyl-Homoserine Lactones in Strain MOLA 401, a MarineFrontiers in microbiology · 2017Article
- Potential Emergence of Multi-quorum Sensing Inhibitor Resistant (MQSIR) Bacteria.Indian journal of microbiology · 2016Review
- The Sinorhizobium meliloti SyrM regulon: effects on global gene expression are mediated by syrA and nodD3.Journal of bacteriology · 2015Article
- The quorum sensing regulator CinR hierarchically regulates two other quorum sensing pathways in ligand-dependent and -independent fashions in Rhizobium etli.Journal of bacteriology · 2015Article
- A nonpyrrolysine member of the widely distributed trimethylamine methyltransferase family is a glycine betaine methyltransferase.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- RNA sequencing analysis of the broad-host-range strain Sinorhizobium fredii NGR234 identifies a large set of genes linked to quorum sensing-dependent regulation in the background of a traI and ngrI deletion mutant.Applied and environmental microbiology · 2014Article
- Rhizobial galactoglucan determines the predatory pattern of Myxococcus xanthus and protects Sinorhizobium meliloti from predation.Environmental microbiology · 2014Article
- Entropy-driven motility of Sinorhizobium meliloti on a semi-solid surface.Proceedings. Biological sciences · 2014Article
- ExpR coordinates the expression of symbiotically important, bundle-forming Flp pili with quorum sensing in Sinorhizobium meliloti.Applied and environmental microbiology · 2014Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Quorum sensing (QS) in Sinorhizobium meliloti, the N-fixing bacterial symbiont of Medicago host plants, involves at least half a dozen different N-acyl homoserine lactone (AHL) signals and perhaps an equal number of AHL receptors. The accumulation of 55 proteins was found to be dependent on SinI, the AHL synthase, and/or on ExpR, one of the AHL receptors. Gas chromatography-mass spectrometry and electrospray ionization tandem mass spectrometry identified 3-oxo-C(14)-homoserine lactone (3-oxo-C(14)-HSL), C(16)-HSL, 3-oxo-C(16)-HSL, C(16:1)-HSL, and 3-oxo-C(16:1)-HSL as the sinI-dependent AHL QS signals accumulated by the 8530 expR(+) strain under the conditions used for proteome analysis. The 8530 expR(+) strain secretes additional, unidentified QS-active compounds. Addition of 200 nM C(14)-HSL or C(16:1)-HSL, two of the known SinI AHLs, affected the levels of 75% of the proteins, confirming that their accumulation is QS regulated. A number of the QS-regulated proteins have functions plausibly related to symbiotic interactions with the host, including ExpE6, IdhA, MocB, Gor, PckA, LeuC, and AglE. Seven of 10 single-crossover beta-glucuronidase (GUS) transcriptional reporters in genes corresponding to QS-regulated proteins showed significantly different activities in the sinI and expR mutant backgrounds and in response to added SinI AHLs. The sinI mutant and several of the single-crossover strains were significantly delayed in the ability to initiate nodules on the primary root of the host plant, Medicago truncatula, indicating that sinI-dependent QS regulation and QS-regulated proteins contribute importantly to the rate or efficiency of nodule initiation. The sinI and expR mutants were also defective in surface swarming motility. The sinI mutant was restored to normal swarming by 5 nM C(16:1)-HSL.
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