ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2005
A polymorphism of intercellular adhesion molecule-1 is associated with a reduced incidence of nonmalarial febrile illness in Kenyan children.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children.Malaria journal · 2023Trial
- TheHeart (British Cardiac Society) · 2025Article
- Missense Genetic Variation of ICAM1 and Incident Heart Failure.Journal of cardiac failure · 2023Article
- Review
- ICAM-1Malaria journal · 2022Article
- Pathophysiology and neurologic sequelae of cerebral malaria.Malaria journal · 2020Review
- Measuring soluble ICAM-1 in African populations.PloS one · 2014Article
- KE and EE genotypes of ICAM-1 gene K469E polymorphism is associated with severe preeclampsia.Disease markers · 2014Article
- The host genetic diversity in malaria infection.Journal of tropical medicine · 2012Article
- Malaria: modification of the red blood cell and consequences in the human host.British journal of haematology · 2011Review
- Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome.PloS one · 2011Article
- Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda.Malaria journal · 2010Article
- Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications.Expert reviews in molecular medicine · 2009Review
- Variation in the ICAM1 gene is not associated with severe malaria phenotypes.Genes and immunity · 2008Article
- Plasmodium falciparum intercellular adhesion molecule-1-based cytoadherence-related signaling in human endothelial cells.The Journal of infectious diseases · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
An intercellular adhesion molecule-1 polymorphism (ICAM-1(Kilifi)) is present at a high frequency across sub-Saharan Africa, and its presence may increase susceptibility to cerebral malaria. Here, we report that, compared with children in whom wild-type intercellular adhesion molecule-1 is present, the incidence of nonmalarial fever is significantly lower among those homozygous for ICAM-1(Kilifi). We propose that ICAM-1(Kilifi) may be associated with reduced rates of tissue damage and of death due to sepsis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.