ReviewThe Journal of experimental medicine2005
The many roads to cross-presentation.
Review in The Journal of experimental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 94 citations in OpenAlex.
- Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka.Clinical proteomics · 2024Article
- Proteome profiling of cutaneous leishmaniasis lesions due to dermotropicbioRxiv : the preprint server for biology · 2024Article
- Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients.International journal of molecular sciences · 2020Review
- Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8Scientific reports · 2017Article
- Expression, Polyubiquitination, and Therapeutic Potential of Recombinant E6E7 from HPV16 Antigens Fused to Ubiquitin.Molecular biotechnology · 2017Article
- Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.Oncoimmunology · 2013Article
- MHC class I antigen presentation of DRiP-derived peptides from a model antigen is not dependent on the AAA ATPase p97.PloS one · 2013Article
- Murine spleen contains a diversity of myeloid and dendritic cells distinct in antigen presenting function.Journal of cellular and molecular medicine · 2012Review
- Immunomodulatory Effects of Hypocrellin A on MHC-restricted Antigen Processing.Immune network · 2011Article
- Article
- Influenza virus inactivation for studies of antigenicity and phenotypic neuraminidase inhibitor resistance profiling.Journal of clinical microbiology · 2010Article
- Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Sec22b is a negative regulator of phagocytosis in macrophages.Molecular biology of the cell · 2009Article
- Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo.Cancer immunology, immunotherapy : CII · 2009Article
- Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Comparing pooled peptides with intact protein for accessing cross-presentation pathways for protective CD8+ and CD4+ T cells.The Journal of biological chemistry · 2009Article
- MHC class I assembly: out and about.Trends in immunology · 2008Review
- Identification of CIITA regulated genetic module dedicated for antigen presentation.PLoS genetics · 2008Article
- MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.Molecular biology of the cell · 2007Article
- Proteasome-independent major histocompatibility complex class I cross-presentation mediated by papaya mosaic virus-like particles leads to expansion of specific human T cells.Journal of virology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cross-presentation of extracellular antigens by MHC class I molecules is required for priming cytotoxic T lymphocytes (CTLs) at locations remote from the site of infection. Various mechanisms have been proposed to explain cross-presentation. One such mechanism involves the fusion of the endoplasmic reticulum (ER) with the endosomal-phagosomal system, in which the machinery required for peptide loading of MHC class I molecules is introduced directly into the phagosome. Here, we discuss the evidence for and against the ER-phagosome concept as well as other possible mechanisms of cross-presentation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.