ArticleClinical practice and epidemiology in mental health : CP & EMH2005
A case control study on psychiatric disorders in Hashimoto disease and Euthyroid Goitre: not only depressive but also anxiety disorders are associated with thyroid autoimmunity.
Article in Clinical practice and epidemiology in mental health : CP & EMH, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis: A Systematic Review and Meta-analysis.JAMA psychiatry · 2018Pooled it
- The effect of photobiomodulation therapy on fatigue and behavioural status in patients with Hashimoto's thyroiditis.Lasers in medical science · 2026Trial
- The evaluation of Hashimoto's thyroiditis with event-related potentials and magnetic resonance spectroscopy and its relation to cognitive function.Scientific reports · 2021Trial
- The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults.Frontiers in psychiatry · 2026Article
- Exploring the mental health challenges of children with autoimmune thyroiditis.BMC pediatrics · 2025Article
- Impact of Pre-lockdown Hyper-energy on Mood and Rhythm Dysregulation in Older Adults During the COVID-19 Pandemic.Clinical practice and epidemiology in mental health : CP & EMH · 2025Article
- Association between small intestine bacterial overgrowth and psychiatric disorders.Frontiers in endocrinology · 2024Review
- Review
- Influence of Thyroid Disorders upon the Incidence and the Severity of Psychosomatic Symptoms in Patients.Iranian journal of public health · 2022Article
- Synaptic loss in a mouse model of euthyroid Hashimoto's thyroiditis: possible involvement of the microglia.BMC neuroscience · 2022Article
- Depression and Autoimmune Hypothyroidism-Their Relationship and the Effects of Treating Psychiatric and Thyroid Disorders on Changes in Clinical and Biochemical Parameters Including BDNF and Other Cytokines-A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2022Review
- The Impact of the COVID-19 Pandemic on Psychological Health and Insomnia among People with Chronic Diseases.Journal of clinical medicine · 2021Article
- Assessment of Visual and Brainstem Auditory Evoked Potentials in Patients with Hashimoto's Thyroiditis.Journal of immunology research · 2021Article
- Rapid cycling bipolar disorder is associated with antithyroid antibodies, instead of thyroid dysfunction.BMC psychiatry · 2019Article
- Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Review
- Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice.Journal of neuroinflammation · 2018Article
- Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients.European archives of psychiatry and clinical neuroscience · 2015Article
- Evidence for a dysregulated immune system in the etiology of psychiatric disorders.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2013Review
- A pattern of cerebral perfusion anomalies between major depressive disorder and Hashimoto thyroiditis.BMC psychiatry · 2011Article
- Effects of hyperthyroidism, hypothyroidism, and thyroid autoimmunity on female sexual function.Journal of endocrinological investigation · 2011Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association between mood and anxiety disorders in Hashimoto disease and Euthyroid Goitre in a case control study.
methodsCases included 19 subjects with Hashimoto disease in euthyroid phase, 19 subjects with euthyroid goitre, 2 control groups each of 76 subjects matched (4/1) according to age and sex drawn from the data base of a community based sample. Psychiatric diagnoses were formulated using the International Composite Diagnostic Interview Simplified, according to DSM-IV criteria. All subjects underwent a complete thyroid evaluation including physical examination, thyroid echography and measure of serum free T4 (FT4), free T3 (FT3), thyroid-stimulating hormone (TSH) and anti-thyroid peroxidase autoantibodies (anti-TPO).
resultsSubjects with Hashimoto disease showed higher frequencies of lifetime Depressive Episode (OR = 6.6, C.L. 95% 1.2-25.7), Generalized Anxiety Disorders (OR = 4,9 Cl 95% 1.5-25.4) and Social Phobia (OR = 20.0, CL 95% 2.3-153.3) whilst no differences were found between subjects with goitre and controls.
conclusionThe study seems to confirm that risk for depressive disorders in subjects with thyroiditis is independent of the thyroid function detected by routine tests and indicates that not only mood but also anxiety disorders may be associated with Hashimoto disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.