ArticleBiophysical journal2006
Melanosomes transported by myosin-V in Xenopus melanophores perform slow 35 nm steps.
Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 42 citations in OpenAlex.
- A novel labeling strategy reveals that myosin Va and myosin Vb bind the same dendritically polarized vesicle population.Traffic (Copenhagen, Denmark) · 2020Article
- Unconventional Myosins: How Regulation Meets Function.International journal of molecular sciences · 2019Review
- Single-Nanoparticle Tracking with Angstrom Localization Precision and Microsecond Time Resolution.Biophysical journal · 2018Article
- The role of cytoskeleton networks on lipid-mediated delivery of DNA.Therapeutic delivery · 2013Article
- Article
- Fluorescence techniques to study lipid dynamics.Cold Spring Harbor perspectives in biology · 2011Review
- Mechanical properties of organelles driven by microtubule-dependent molecular motors in living cells.PloS one · 2011Article
- Principles of unconventional myosin function and targeting.Annual review of cell and developmental biology · 2011Review
- ParticleStats: open source software for the analysis of particle motility and cytoskeletal polarity.Nucleic acids research · 2010Article
- Anomalous dynamics of melanosomes driven by myosin-V in Xenopus laevis melanophores.Biophysical journal · 2009Article
- Random walk of processive, quantum dot-labeled myosin Va molecules within the actin cortex of COS-7 cells.Biophysical journal · 2009Article
- Velocity, processivity, and individual steps of single myosin V molecules in live cells.Biophysical journal · 2009Article
- A comparison of step-detection methods: how well can you do?Biophysical journal · 2008Article
- Myosin va mediates docking of secretory granules at the plasma membrane.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- Stepwise movements in vesicle transport of HER2 by motor proteins in living cells.Biophysical journal · 2007Article
- Tracking melanosomes inside a cell to study molecular motors and their interaction.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
We studied the motion of pigment organelles driven by myosin-V in Xenopus melanophores using a tracking technique with precision of 2 nm. The organelle trajectories showed occasional steps with a distribution centered at 35 nm and a standard deviation of 13 nm, in agreement with the step size of myosin-V determined in vitro. In contrast, trajectories of melanosomes in cells expressing a dominant negative form of myosin-V did not show steps. The step duration was in the range 20-80 ms, slower than what it would be expected from in vitro results. We speculate that the cytoplasm high viscosity may affect significantly the melanosomes' motion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.