Evidence map›Paper›PMID 16284272›Full record

ArticleBiophysical journal2006

Optical readout of gold nanoparticle-based DNA microarrays without silver enhancement.

Gerhard A Blab, Laurent Cognet, Stéphane Berciaud, Isabelle Alexandre, Dieter Husar, José Remacle, Brahim Lounis

Abstract readLetter
In one paragraph

Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gerhard A Blab
Laurent Cognet
Stéphane Berciaud
Isabelle Alexandre
Dieter Husar
José Remacle
Brahim Lounis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a novel readout scheme for gold nanoparticle-based DNA microarrays relying on "Laser-Induced Scattering around a NanoAbsorber". It provides direct counting of individual nanoparticles present on each array spot and stable signals, without any silver enhancement. Given the detection of nanometer-sized particles, which minimize the steric hindrance, the linear dynamic range of the method is particularly large and well suited for microarray detection.

Indexed as

AcousticsDNAGoldLasersMicroscopy, FluorescenceNanostructuresNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisOptics and PhotonicsReproducibility of ResultsSensitivity and SpecificitySilverDNAGoldSilver

Identifiers

PMID16284272
PMCPMC1367045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.